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Mitochondrial complex I abnormalities is associated with tau and clinical symptoms in mild Alzheimer’s disease
BACKGROUND: Mitochondrial electron transport chain abnormalities have been reported in postmortem pathological specimens of Alzheimer’s disease (AD). However, it remains unclear how amyloid and tau are associated with mitochondrial dysfunction in vivo. The purpose of this study is to assess the loca...
Autores principales: | Terada, Tatsuhiro, Therriault, Joseph, Kang, Min Su Peter, Savard, Melissa, Pascoal, Tharick Ali, Lussier, Firoza, Tissot, Cecile, Wang, Yi-Ting, Benedet, Andrea, Matsudaira, Takashi, Bunai, Tomoyasu, Obi, Tomokazu, Tsukada, Hideo, Ouchi, Yasuomi, Rosa-Neto, Pedro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8074456/ https://www.ncbi.nlm.nih.gov/pubmed/33902654 http://dx.doi.org/10.1186/s13024-021-00448-1 |
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