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Mitochondrial complex I abnormalities is associated with tau and clinical symptoms in mild Alzheimer’s disease

BACKGROUND: Mitochondrial electron transport chain abnormalities have been reported in postmortem pathological specimens of Alzheimer’s disease (AD). However, it remains unclear how amyloid and tau are associated with mitochondrial dysfunction in vivo. The purpose of this study is to assess the loca...

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Detalles Bibliográficos
Autores principales: Terada, Tatsuhiro, Therriault, Joseph, Kang, Min Su Peter, Savard, Melissa, Pascoal, Tharick Ali, Lussier, Firoza, Tissot, Cecile, Wang, Yi-Ting, Benedet, Andrea, Matsudaira, Takashi, Bunai, Tomoyasu, Obi, Tomokazu, Tsukada, Hideo, Ouchi, Yasuomi, Rosa-Neto, Pedro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8074456/
https://www.ncbi.nlm.nih.gov/pubmed/33902654
http://dx.doi.org/10.1186/s13024-021-00448-1

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