Experimental and natural evidence of SARS-CoV-2-infection-induced activation of type I interferon responses

Type I interferons (IFNs) are our first line of defense against virus infection. Recent studies have suggested the ability of SARS-CoV-2 proteins to inhibit IFN responses. Emerging data also suggest that timing and extent of IFN production is associated with manifestation of COVID-19 severity. In sp...

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Detalles Bibliográficos
Autores principales: Banerjee, Arinjay, El-Sayes, Nader, Budylowski, Patrick, Jacob, Rajesh Abraham, Richard, Daniel, Maan, Hassaan, Aguiar, Jennifer A., Demian, Wael L., Baid, Kaushal, D'Agostino, Michael R., Ang, Jann Catherine, Murdza, Tetyana, Tremblay, Benjamin J.-M., Afkhami, Sam, Karimzadeh, Mehran, Irving, Aaron T., Yip, Lily, Ostrowski, Mario, Hirota, Jeremy A., Kozak, Robert, Capellini, Terence D., Miller, Matthew S., Wang, Bo, Mubareka, Samira, McGeer, Allison J., McArthur, Andrew G., Doxey, Andrew C., Mossman, Karen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8074517/
https://www.ncbi.nlm.nih.gov/pubmed/33937724
http://dx.doi.org/10.1016/j.isci.2021.102477

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