Down-Regulation of the Proteoglycan Decorin Fills in the Tumor-Promoting Phenotype of Ionizing Radiation-Induced Senescent Human Breast Stromal Fibroblasts

SIMPLE SUMMARY: Ionizing radiation (a typical remedy for breast cancer) results in the premature senescence of the adjacent to the neoplastic cells stromal fibroblasts. Here, we showed that these senescent fibroblasts are characterized by the down-regulation of the small leucine-rich proteoglycan de...

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Detalles Bibliográficos
Autores principales: Mavrogonatou, Eleni, Papadopoulou, Adamantia, Fotopoulou, Asimina, Tsimelis, Stathis, Bassiony, Heba, Yiacoumettis, Andreas M., Panagiotou, Petros N., Pratsinis, Harris, Kletsas, Dimitris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8074608/
https://www.ncbi.nlm.nih.gov/pubmed/33924197
http://dx.doi.org/10.3390/cancers13081987

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