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The Association between Migraine and Abdominal Aortic Aneurysms: A Nationwide Population-Based Cohort Study
Previous studies have indicated that patients with migraine have a higher prevalence of risk factors known to be associated with cardiovascular diseases. There are also shared epidemiology and molecular mechanisms between migraine and abdominal aortic aneurysm (AAA). We hypothesized that patients wi...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8074774/ https://www.ncbi.nlm.nih.gov/pubmed/33924263 http://dx.doi.org/10.3390/ijerph18084389 |
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author | Lin, Jou-Yu Tung, Che-Se Wang, Jen-Chun Chien, Wu-Chien Chung, Chi-Hsiang Lin, Chih-Yuan Tsai, Shih-Hung |
author_facet | Lin, Jou-Yu Tung, Che-Se Wang, Jen-Chun Chien, Wu-Chien Chung, Chi-Hsiang Lin, Chih-Yuan Tsai, Shih-Hung |
author_sort | Lin, Jou-Yu |
collection | PubMed |
description | Previous studies have indicated that patients with migraine have a higher prevalence of risk factors known to be associated with cardiovascular diseases. There are also shared epidemiology and molecular mechanisms between migraine and abdominal aortic aneurysm (AAA). We hypothesized that patients with migraine could have an increased risk of AAA. To test this hypothesis, we used the National Health Insurance Research Database (NHIRD) to evaluate whether associations exist between migraine and AAA. The data for this nationwide population-based retrospective cohort study were obtained from the NHIRD in Taiwan. The assessed study outcome was the cumulative incidence of AAA in patients with migraine during a 15-year follow-up period. Among the 1,936,512 patients from the NHIRD, 53,668 (2.77%) patients were identified as having been diagnosed with migraine. The patients with migraine had a significantly higher cumulative risk of 3.558 of developing an AAA 5 years after the index date compared with the patients without migraine. At the end of the 15-year follow-up period, a significantly higher incidence of AAA (0.98%) was observed in the patients with migraine than in those without migraine (0.24%). We revealed an association between the development of migraine and AAA. |
format | Online Article Text |
id | pubmed-8074774 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-80747742021-04-27 The Association between Migraine and Abdominal Aortic Aneurysms: A Nationwide Population-Based Cohort Study Lin, Jou-Yu Tung, Che-Se Wang, Jen-Chun Chien, Wu-Chien Chung, Chi-Hsiang Lin, Chih-Yuan Tsai, Shih-Hung Int J Environ Res Public Health Article Previous studies have indicated that patients with migraine have a higher prevalence of risk factors known to be associated with cardiovascular diseases. There are also shared epidemiology and molecular mechanisms between migraine and abdominal aortic aneurysm (AAA). We hypothesized that patients with migraine could have an increased risk of AAA. To test this hypothesis, we used the National Health Insurance Research Database (NHIRD) to evaluate whether associations exist between migraine and AAA. The data for this nationwide population-based retrospective cohort study were obtained from the NHIRD in Taiwan. The assessed study outcome was the cumulative incidence of AAA in patients with migraine during a 15-year follow-up period. Among the 1,936,512 patients from the NHIRD, 53,668 (2.77%) patients were identified as having been diagnosed with migraine. The patients with migraine had a significantly higher cumulative risk of 3.558 of developing an AAA 5 years after the index date compared with the patients without migraine. At the end of the 15-year follow-up period, a significantly higher incidence of AAA (0.98%) was observed in the patients with migraine than in those without migraine (0.24%). We revealed an association between the development of migraine and AAA. MDPI 2021-04-20 /pmc/articles/PMC8074774/ /pubmed/33924263 http://dx.doi.org/10.3390/ijerph18084389 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Lin, Jou-Yu Tung, Che-Se Wang, Jen-Chun Chien, Wu-Chien Chung, Chi-Hsiang Lin, Chih-Yuan Tsai, Shih-Hung The Association between Migraine and Abdominal Aortic Aneurysms: A Nationwide Population-Based Cohort Study |
title | The Association between Migraine and Abdominal Aortic Aneurysms: A Nationwide Population-Based Cohort Study |
title_full | The Association between Migraine and Abdominal Aortic Aneurysms: A Nationwide Population-Based Cohort Study |
title_fullStr | The Association between Migraine and Abdominal Aortic Aneurysms: A Nationwide Population-Based Cohort Study |
title_full_unstemmed | The Association between Migraine and Abdominal Aortic Aneurysms: A Nationwide Population-Based Cohort Study |
title_short | The Association between Migraine and Abdominal Aortic Aneurysms: A Nationwide Population-Based Cohort Study |
title_sort | association between migraine and abdominal aortic aneurysms: a nationwide population-based cohort study |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8074774/ https://www.ncbi.nlm.nih.gov/pubmed/33924263 http://dx.doi.org/10.3390/ijerph18084389 |
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