Cargando…

Efficacy and Safety of Inhalation Sedation during Office Probing for Congenital Nasolacrimal Duct Obstruction

We compared the effectiveness of inhaled sevoflurane versus physical restraint during probing in children with congenital nasolacrimal duct obstruction (CNLDO). We performed a retrospective review of children with CNLDO who underwent office probing procedures by a single surgeon under sedation or re...

Descripción completa

Detalles Bibliográficos
Autores principales: Lee, Chunghyun, Jeong, Su-Min, Kim, Gye Jung, Joo, Eun-Young, Song, Myung Hee, Sa, Ho-Seok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8074913/
https://www.ncbi.nlm.nih.gov/pubmed/33924278
http://dx.doi.org/10.3390/jcm10081800
_version_ 1783684446737661952
author Lee, Chunghyun
Jeong, Su-Min
Kim, Gye Jung
Joo, Eun-Young
Song, Myung Hee
Sa, Ho-Seok
author_facet Lee, Chunghyun
Jeong, Su-Min
Kim, Gye Jung
Joo, Eun-Young
Song, Myung Hee
Sa, Ho-Seok
author_sort Lee, Chunghyun
collection PubMed
description We compared the effectiveness of inhaled sevoflurane versus physical restraint during probing in children with congenital nasolacrimal duct obstruction (CNLDO). We performed a retrospective review of children with CNLDO who underwent office probing procedures by a single surgeon under sedation or restraint. Patients’ characteristics at the time of probing, including age, sex, laterality, previous non-surgical treatment, presence of dacryocystitis, outcomes of probing, and complications were compared between the sedation and restraint groups. A multivariable logistic regression analysis was performed to investigate the prognostic factors associated with the success of probing. A subgroup analysis by 12 months of age was also conducted. The overall success rate was 88.6% in 202 eyes of 180 consecutive children (mean age, 15.1 ± 7.7 months). The sedation group had a marginally higher success rates than the restraint group (93.8% vs. 85.1%, p = 0.056). The success rate was not significantly different between the two groups in children aged <12 months (90.9% vs. 93.1%, p = 0.739), but it was significantly higher in the sedation group (94.7% vs. 77.8%. p = 0.006) in children aged ≥12 months. Inhalation sedation was the most potent factor associated with success (adjusted odds ratio = 5.56, 95% confidence interval = 1.33–23.13, p = 0.018) in children aged ≥12 months. There were no surgical or sedation-related complications intra- and postoperatively. Inhaled sevoflurane sedation resulted in more successful, controlled, painless probing, particularly in children aged ≥12 months. It represents a safe, efficient alternative to general anesthesia.
format Online
Article
Text
id pubmed-8074913
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-80749132021-04-27 Efficacy and Safety of Inhalation Sedation during Office Probing for Congenital Nasolacrimal Duct Obstruction Lee, Chunghyun Jeong, Su-Min Kim, Gye Jung Joo, Eun-Young Song, Myung Hee Sa, Ho-Seok J Clin Med Article We compared the effectiveness of inhaled sevoflurane versus physical restraint during probing in children with congenital nasolacrimal duct obstruction (CNLDO). We performed a retrospective review of children with CNLDO who underwent office probing procedures by a single surgeon under sedation or restraint. Patients’ characteristics at the time of probing, including age, sex, laterality, previous non-surgical treatment, presence of dacryocystitis, outcomes of probing, and complications were compared between the sedation and restraint groups. A multivariable logistic regression analysis was performed to investigate the prognostic factors associated with the success of probing. A subgroup analysis by 12 months of age was also conducted. The overall success rate was 88.6% in 202 eyes of 180 consecutive children (mean age, 15.1 ± 7.7 months). The sedation group had a marginally higher success rates than the restraint group (93.8% vs. 85.1%, p = 0.056). The success rate was not significantly different between the two groups in children aged <12 months (90.9% vs. 93.1%, p = 0.739), but it was significantly higher in the sedation group (94.7% vs. 77.8%. p = 0.006) in children aged ≥12 months. Inhalation sedation was the most potent factor associated with success (adjusted odds ratio = 5.56, 95% confidence interval = 1.33–23.13, p = 0.018) in children aged ≥12 months. There were no surgical or sedation-related complications intra- and postoperatively. Inhaled sevoflurane sedation resulted in more successful, controlled, painless probing, particularly in children aged ≥12 months. It represents a safe, efficient alternative to general anesthesia. MDPI 2021-04-20 /pmc/articles/PMC8074913/ /pubmed/33924278 http://dx.doi.org/10.3390/jcm10081800 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Lee, Chunghyun
Jeong, Su-Min
Kim, Gye Jung
Joo, Eun-Young
Song, Myung Hee
Sa, Ho-Seok
Efficacy and Safety of Inhalation Sedation during Office Probing for Congenital Nasolacrimal Duct Obstruction
title Efficacy and Safety of Inhalation Sedation during Office Probing for Congenital Nasolacrimal Duct Obstruction
title_full Efficacy and Safety of Inhalation Sedation during Office Probing for Congenital Nasolacrimal Duct Obstruction
title_fullStr Efficacy and Safety of Inhalation Sedation during Office Probing for Congenital Nasolacrimal Duct Obstruction
title_full_unstemmed Efficacy and Safety of Inhalation Sedation during Office Probing for Congenital Nasolacrimal Duct Obstruction
title_short Efficacy and Safety of Inhalation Sedation during Office Probing for Congenital Nasolacrimal Duct Obstruction
title_sort efficacy and safety of inhalation sedation during office probing for congenital nasolacrimal duct obstruction
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8074913/
https://www.ncbi.nlm.nih.gov/pubmed/33924278
http://dx.doi.org/10.3390/jcm10081800
work_keys_str_mv AT leechunghyun efficacyandsafetyofinhalationsedationduringofficeprobingforcongenitalnasolacrimalductobstruction
AT jeongsumin efficacyandsafetyofinhalationsedationduringofficeprobingforcongenitalnasolacrimalductobstruction
AT kimgyejung efficacyandsafetyofinhalationsedationduringofficeprobingforcongenitalnasolacrimalductobstruction
AT jooeunyoung efficacyandsafetyofinhalationsedationduringofficeprobingforcongenitalnasolacrimalductobstruction
AT songmyunghee efficacyandsafetyofinhalationsedationduringofficeprobingforcongenitalnasolacrimalductobstruction
AT sahoseok efficacyandsafetyofinhalationsedationduringofficeprobingforcongenitalnasolacrimalductobstruction