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Estimating COVID-19 cases and outbreaks on-stream through phone calls

One of the main problems in controlling COVID-19 epidemic spread is the delay in confirming cases. Having information on changes in the epidemic evolution or outbreaks rise before laboratory-confirmation is crucial in decision making for Public Health policies. We present an algorithm to estimate on...

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Autores principales: Alvarez, Ezequiel, Obando, Daniela, Crespo, Sebastian, Garcia, Enio, Kreplak, Nicolas, Marsico, Franco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8074976/
https://www.ncbi.nlm.nih.gov/pubmed/33959370
http://dx.doi.org/10.1098/rsos.202312
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author Alvarez, Ezequiel
Obando, Daniela
Crespo, Sebastian
Garcia, Enio
Kreplak, Nicolas
Marsico, Franco
author_facet Alvarez, Ezequiel
Obando, Daniela
Crespo, Sebastian
Garcia, Enio
Kreplak, Nicolas
Marsico, Franco
author_sort Alvarez, Ezequiel
collection PubMed
description One of the main problems in controlling COVID-19 epidemic spread is the delay in confirming cases. Having information on changes in the epidemic evolution or outbreaks rise before laboratory-confirmation is crucial in decision making for Public Health policies. We present an algorithm to estimate on-stream the number of COVID-19 cases using the data from telephone calls to a COVID-line. By modelling the calls as background (proportional to population) plus signal (proportional to infected), we fit the calls in Province of Buenos Aires (Argentina) with coefficient of determination R(2) > 0.85. This result allows us to estimate the number of cases given the number of calls from a specific district, days before the laboratory results are available. We validate the algorithm with real data. We show how to use the algorithm to track on-stream the epidemic, and present the Early Outbreak Alarm to detect outbreaks in advance of laboratory results. One key point in the developed algorithm is a detailed track of the uncertainties in the estimations, since the alarm uses the significance of the observables as a main indicator to detect an anomaly. We present the details of the explicit example in Villa Azul (Quilmes) where this tool resulted crucial to control an outbreak on time. The presented tools have been designed in urgency with the available data at the time of the development, and therefore have their limitations which we describe and discuss. We consider possible improvements on the tools, many of which are currently under development.
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spelling pubmed-80749762021-05-05 Estimating COVID-19 cases and outbreaks on-stream through phone calls Alvarez, Ezequiel Obando, Daniela Crespo, Sebastian Garcia, Enio Kreplak, Nicolas Marsico, Franco R Soc Open Sci Mathematics One of the main problems in controlling COVID-19 epidemic spread is the delay in confirming cases. Having information on changes in the epidemic evolution or outbreaks rise before laboratory-confirmation is crucial in decision making for Public Health policies. We present an algorithm to estimate on-stream the number of COVID-19 cases using the data from telephone calls to a COVID-line. By modelling the calls as background (proportional to population) plus signal (proportional to infected), we fit the calls in Province of Buenos Aires (Argentina) with coefficient of determination R(2) > 0.85. This result allows us to estimate the number of cases given the number of calls from a specific district, days before the laboratory results are available. We validate the algorithm with real data. We show how to use the algorithm to track on-stream the epidemic, and present the Early Outbreak Alarm to detect outbreaks in advance of laboratory results. One key point in the developed algorithm is a detailed track of the uncertainties in the estimations, since the alarm uses the significance of the observables as a main indicator to detect an anomaly. We present the details of the explicit example in Villa Azul (Quilmes) where this tool resulted crucial to control an outbreak on time. The presented tools have been designed in urgency with the available data at the time of the development, and therefore have their limitations which we describe and discuss. We consider possible improvements on the tools, many of which are currently under development. The Royal Society 2021-03-17 /pmc/articles/PMC8074976/ /pubmed/33959370 http://dx.doi.org/10.1098/rsos.202312 Text en © 2021 The Authors. https://creativecommons.org/licenses/by/4.0/Published by the Royal Society under the terms of the Creative Commons Attribution License http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, provided the original author and source are credited.
spellingShingle Mathematics
Alvarez, Ezequiel
Obando, Daniela
Crespo, Sebastian
Garcia, Enio
Kreplak, Nicolas
Marsico, Franco
Estimating COVID-19 cases and outbreaks on-stream through phone calls
title Estimating COVID-19 cases and outbreaks on-stream through phone calls
title_full Estimating COVID-19 cases and outbreaks on-stream through phone calls
title_fullStr Estimating COVID-19 cases and outbreaks on-stream through phone calls
title_full_unstemmed Estimating COVID-19 cases and outbreaks on-stream through phone calls
title_short Estimating COVID-19 cases and outbreaks on-stream through phone calls
title_sort estimating covid-19 cases and outbreaks on-stream through phone calls
topic Mathematics
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8074976/
https://www.ncbi.nlm.nih.gov/pubmed/33959370
http://dx.doi.org/10.1098/rsos.202312
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