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Safety assessment of multiple repeated percutaneous punctures for the collection of cerebrospinal fluid in rats

The objective of this study was to examine the safety of multiple repeated percutaneous punctures of cisterna magna for collecting cerebrospinal fluid (CSF) and preliminarily determine the optimal time interval and volume at each collection. Sixty Wistar rats were randomly assigned to six groups: 10...

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Detalles Bibliográficos
Autores principales: Wang, Dongxue, Zhao, Ying, Yang, Yang, Xie, Hailong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Associação Brasileira de Divulgação Científica 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8075127/
https://www.ncbi.nlm.nih.gov/pubmed/33909853
http://dx.doi.org/10.1590/1414-431X202010032