Naïve CD4+ T Cell Lymphopenia and Apoptosis in Chronic Hepatitis C Virus Infection Is Driven by the CD31+ Subset and Is Partially Normalized in Direct-Acting Antiviral Treated Persons

BACKGROUND: The mechanisms underlying naïve CD4+ lymphopenia during chronic Hepatitis C Virus (HCV) infection are unclear. Whether direct-acting antiviral (DAA) therapy restores peripheral naïve CD4+ T cell numbers and function is unknown. METHODS: We enumerated frequencies and counts of peripheral...

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Detalles Bibliográficos
Autores principales: Auma, Ann W.N., Shive, Carey L., Lange, Alyssa, Damjanovska, Sofi, Kowal, Corinne, Zebrowski, Elizabeth, Pandiyan, Pushpa, Wilson, Brigid, Kalayjian, Robert C., Canaday, David H., Anthony, Donald D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8075159/
https://www.ncbi.nlm.nih.gov/pubmed/33912168
http://dx.doi.org/10.3389/fimmu.2021.641230

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8075159/
https://www.ncbi.nlm.nih.gov/pubmed/33912168
http://dx.doi.org/10.3389/fimmu.2021.641230

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