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The phase space of meaning model of psychopathology: A computer simulation modelling study

INTRODUCTION: The hypothesis of a general psychopathology factor that underpins all common forms of mental disorders has been gaining momentum in contemporary clinical research and is known as the p factor hypothesis. Recently, a semiotic, embodied, and psychoanalytic conceptualisation of the p fact...

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Autores principales: Kleinbub, Johann Roland, Testolin, Alberto, Palmieri, Arianna, Salvatore, Sergio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8075201/
https://www.ncbi.nlm.nih.gov/pubmed/33901183
http://dx.doi.org/10.1371/journal.pone.0249320
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author Kleinbub, Johann Roland
Testolin, Alberto
Palmieri, Arianna
Salvatore, Sergio
author_facet Kleinbub, Johann Roland
Testolin, Alberto
Palmieri, Arianna
Salvatore, Sergio
author_sort Kleinbub, Johann Roland
collection PubMed
description INTRODUCTION: The hypothesis of a general psychopathology factor that underpins all common forms of mental disorders has been gaining momentum in contemporary clinical research and is known as the p factor hypothesis. Recently, a semiotic, embodied, and psychoanalytic conceptualisation of the p factor has been proposed called the Harmonium Model, which provides a computational account of such a construct. This research tested the core tenet of the Harmonium model, which is the idea that psychopathology can be conceptualised as due to poorly-modulable cognitive processes, and modelled the concept of Phase Space of Meaning (PSM) at the computational level. METHOD: Two studies were performed, both based on a simulation design implementing a deep learning model, simulating a cognitive process: a classification task. The level of performance of the task was considered the simulated equivalent to the normality-psychopathology continuum, the dimensionality of the neural network’s internal computational dynamics being the simulated equivalent of the PSM’s dimensionality. RESULTS: The neural networks’ level of performance was shown to be associated with the characteristics of the internal computational dynamics, assumed to be the simulated equivalent of poorly-modulable cognitive processes. DISCUSSION: Findings supported the hypothesis. They showed that the neural network’s low performance was a matter of the combination of predicted characteristics of the neural networks’ internal computational dynamics. Implications, limitations, and further research directions are discussed.
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spelling pubmed-80752012021-05-05 The phase space of meaning model of psychopathology: A computer simulation modelling study Kleinbub, Johann Roland Testolin, Alberto Palmieri, Arianna Salvatore, Sergio PLoS One Research Article INTRODUCTION: The hypothesis of a general psychopathology factor that underpins all common forms of mental disorders has been gaining momentum in contemporary clinical research and is known as the p factor hypothesis. Recently, a semiotic, embodied, and psychoanalytic conceptualisation of the p factor has been proposed called the Harmonium Model, which provides a computational account of such a construct. This research tested the core tenet of the Harmonium model, which is the idea that psychopathology can be conceptualised as due to poorly-modulable cognitive processes, and modelled the concept of Phase Space of Meaning (PSM) at the computational level. METHOD: Two studies were performed, both based on a simulation design implementing a deep learning model, simulating a cognitive process: a classification task. The level of performance of the task was considered the simulated equivalent to the normality-psychopathology continuum, the dimensionality of the neural network’s internal computational dynamics being the simulated equivalent of the PSM’s dimensionality. RESULTS: The neural networks’ level of performance was shown to be associated with the characteristics of the internal computational dynamics, assumed to be the simulated equivalent of poorly-modulable cognitive processes. DISCUSSION: Findings supported the hypothesis. They showed that the neural network’s low performance was a matter of the combination of predicted characteristics of the neural networks’ internal computational dynamics. Implications, limitations, and further research directions are discussed. Public Library of Science 2021-04-26 /pmc/articles/PMC8075201/ /pubmed/33901183 http://dx.doi.org/10.1371/journal.pone.0249320 Text en © 2021 Kleinbub et al https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Kleinbub, Johann Roland
Testolin, Alberto
Palmieri, Arianna
Salvatore, Sergio
The phase space of meaning model of psychopathology: A computer simulation modelling study
title The phase space of meaning model of psychopathology: A computer simulation modelling study
title_full The phase space of meaning model of psychopathology: A computer simulation modelling study
title_fullStr The phase space of meaning model of psychopathology: A computer simulation modelling study
title_full_unstemmed The phase space of meaning model of psychopathology: A computer simulation modelling study
title_short The phase space of meaning model of psychopathology: A computer simulation modelling study
title_sort phase space of meaning model of psychopathology: a computer simulation modelling study
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8075201/
https://www.ncbi.nlm.nih.gov/pubmed/33901183
http://dx.doi.org/10.1371/journal.pone.0249320
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