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Attenuation of the upregulation of NF-κB and AP-1 DNA-binding activities induced by tunicamycin or hypoxia/reoxygenation in neonatal rat cardiomyocytes by SERCA2a overexpression

The present study aimed to investigate the effects of the overexpression of sarco/endoplasmic reticulum Ca(2+)-ATPase (SERCA2a) on endoplasmic reticulum (ER) stress (ERS)-associated inflammation in neonatal rat cardiomyocytes (NRCMs) induced by tunicamycin (TM) or hypoxia/reoxygenation (H/R). The op...

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Detalles Bibliográficos
Autores principales: Qu, Zhigang, Lu, Xiaochun, Qu, Yan, Tao, Tianqi, Liu, Xiuhua, Li, Xiaoying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8075284/
https://www.ncbi.nlm.nih.gov/pubmed/33907834
http://dx.doi.org/10.3892/ijmm.2021.4946