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Biliverdin Protects Against Cerebral Ischemia/Reperfusion Injury by Regulating the miR-27a-3p/Rgs1 Axis

BACKGROUND: We have previously demonstrated that biliverdin has neuroprotective effects that ameliorate cerebral ischemia/reperfusion (I/R) injury in rats. However, the underlying mechanism is unknown. This study aimed at elucidating on the modulatory role of miR-27a-3p on Rgs1 as a mechanism by whi...

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Detalles Bibliográficos
Autores principales: Li, Junjie, Peng, Lijia, Bai, Wenya, Peng, Peihua, Chen, Wendong, Yang, Wei, Shao, Jianlin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8075361/
https://www.ncbi.nlm.nih.gov/pubmed/33911865
http://dx.doi.org/10.2147/NDT.S300773