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A Systems Biology Approach for Hypothesizing the Effect of Genetic Variants on Neuroimaging Features in Alzheimer’s Disease

BACKGROUND: Neuroimaging markers provide quantitative insight into brain structure and function in neurodegenerative diseases, such as Alzheimer’s disease, where we lack mechanistic insights to explain pathophysiology. These mechanisms are often mediated by genes and genetic variations and are often...

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Detalles Bibliográficos
Autores principales: Golriz Khatami, Sepehr, Domingo-Fernández, Daniel, Mubeen, Sarah, Hoyt, Charles Tapley, Robinson, Christine, Karki, Reagon, Iyappan, Anandhi, Kodamullil, Alpha Tom, Hofmann-Apitius, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8075382/
https://www.ncbi.nlm.nih.gov/pubmed/33554913
http://dx.doi.org/10.3233/JAD-201397