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The Neuroprotective Beta Amyloid Hexapeptide Core Reverses Deficits in Synaptic Plasticity in the 5xFAD APP/PS1 Mouse Model

Alzheimer’s disease (AD) is the most common cause of dementia in the aging population. Evidence implicates elevated soluble oligomeric Aβ as one of the primary triggers during the prodromic phase leading to AD, effected largely via hyperphosphorylation of the microtubule-associated protein tau. At l...

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Detalles Bibliográficos
Autores principales: Forest, Kelly H., Taketa, Ruth, Arora, Komal, Todorovic, Cedomir, Nichols, Robert A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8075567/
https://www.ncbi.nlm.nih.gov/pubmed/33912008
http://dx.doi.org/10.3389/fnmol.2021.576038