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A Step-by-Step Process on Sample Size Determination for Medical Research

Determination of a minimum sample size required for a study is a major consideration which all researchers are confronted with at the early stage of developing a research protocol. This is because the researcher will need to have a sound prerequisite knowledge of inferential statistics in order to e...

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Autor principal: Bujang, Mohamad Adam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Penerbit Universiti Sains Malaysia 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8075593/
https://www.ncbi.nlm.nih.gov/pubmed/33958957
http://dx.doi.org/10.21315/mjms2021.28.2.2
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author Bujang, Mohamad Adam
author_facet Bujang, Mohamad Adam
author_sort Bujang, Mohamad Adam
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description Determination of a minimum sample size required for a study is a major consideration which all researchers are confronted with at the early stage of developing a research protocol. This is because the researcher will need to have a sound prerequisite knowledge of inferential statistics in order to enable him/her to acquire a thorough understanding of the overall concept of a minimum sample size requirement and its estimation. Besides type I error and power of the study, some estimates for effect sizes will also need to be determined in the process to calculate or estimate the sample size. The appropriateness in calculating or estimating the sample size will enable the researchers to better plan their study especially pertaining to recruitment of subjects. To facilitate a researcher in estimating the appropriate sample size for their study, this article provides some recommendations for researchers on how to determine the appropriate sample size for their studies. In addition, several issues related to sample size determination were also discussed.
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spelling pubmed-80755932021-05-05 A Step-by-Step Process on Sample Size Determination for Medical Research Bujang, Mohamad Adam Malays J Med Sci Review Article Determination of a minimum sample size required for a study is a major consideration which all researchers are confronted with at the early stage of developing a research protocol. This is because the researcher will need to have a sound prerequisite knowledge of inferential statistics in order to enable him/her to acquire a thorough understanding of the overall concept of a minimum sample size requirement and its estimation. Besides type I error and power of the study, some estimates for effect sizes will also need to be determined in the process to calculate or estimate the sample size. The appropriateness in calculating or estimating the sample size will enable the researchers to better plan their study especially pertaining to recruitment of subjects. To facilitate a researcher in estimating the appropriate sample size for their study, this article provides some recommendations for researchers on how to determine the appropriate sample size for their studies. In addition, several issues related to sample size determination were also discussed. Penerbit Universiti Sains Malaysia 2021-04 2021-04-21 /pmc/articles/PMC8075593/ /pubmed/33958957 http://dx.doi.org/10.21315/mjms2021.28.2.2 Text en © Penerbit Universiti Sains Malaysia, 2021 https://creativecommons.org/licenses/by/4.0/This work is licensed under the terms of the Creative Commons Attribution (CC BY) (http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) ).
spellingShingle Review Article
Bujang, Mohamad Adam
A Step-by-Step Process on Sample Size Determination for Medical Research
title A Step-by-Step Process on Sample Size Determination for Medical Research
title_full A Step-by-Step Process on Sample Size Determination for Medical Research
title_fullStr A Step-by-Step Process on Sample Size Determination for Medical Research
title_full_unstemmed A Step-by-Step Process on Sample Size Determination for Medical Research
title_short A Step-by-Step Process on Sample Size Determination for Medical Research
title_sort step-by-step process on sample size determination for medical research
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8075593/
https://www.ncbi.nlm.nih.gov/pubmed/33958957
http://dx.doi.org/10.21315/mjms2021.28.2.2
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