Considerations for the discovery and development of 3-chymotrypsin-like cysteine protease inhibitors targeting SARS-CoV-2 infection

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the cause of the COVID-19 pandemic. The coronavirus 3-chymotrypsin-like protease (3CLpro) controls virus replication and is therefore considered a major target and promising opportunity for rational-based antiviral discovery with direct...

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Detalles Bibliográficos
Autores principales: Vandyck, Koen, Deval, Jerome
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8075814/
https://www.ncbi.nlm.nih.gov/pubmed/34029993
http://dx.doi.org/10.1016/j.coviro.2021.04.006

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8075814/
https://www.ncbi.nlm.nih.gov/pubmed/34029993
http://dx.doi.org/10.1016/j.coviro.2021.04.006

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