Epithelial production of elastase is increased in inflammatory bowel disease and causes mucosal inflammation

Imbalance between proteases and their inhibitors plays a crucial role in the development of Inflammatory Bowel Diseases (IBD). Increased elastolytic activity is observed in the colon of patients suffering from IBD. Here, we aimed at identifying the players involved in elastolytic hyperactivity assoc...

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Detalles Bibliográficos
Autores principales: Motta, Jean-Paul, Rolland, Corinne, Edir, Anissa, Florence, Ana-Carolina, Sagnat, David, Bonnart, Chrystelle, Rousset, Perrine, Guiraud, Laura, Quaranta-Nicaise, Muriel, Mas, Emmanuel, Bonnet, Delphine, Verdu, Elena F., McKay, Derek M., Buscail, Etienne, Alric, Laurent, Vergnolle, Nathalie, Deraison, Céline
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8075934/
https://www.ncbi.nlm.nih.gov/pubmed/33674762
http://dx.doi.org/10.1038/s41385-021-00375-w

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