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Genome-wide association study identifies zonisamide responsive gene in Parkinson’s disease patients

Long-term treatment of Parkinson’s disease (PD) by levodopa leads to motor complication “wearing-off”. Zonisamide is a nondopaminergic antiparkinsonian drug that can improve “wearing-off” although response to the treatment varies between individuals. To clarify the genetic basis of zonisamide respon...

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Detalles Bibliográficos
Autores principales: Cha, Pei-Chieng, Satake, Wataru, Ando-Kanagawa, Yuko, Yamamoto, Ken, Murata, Miho, Toda, Tatsushi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Singapore 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8075945/
https://www.ncbi.nlm.nih.gov/pubmed/32355309
http://dx.doi.org/10.1038/s10038-020-0760-8