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Role of the DNA damage response in prostate cancer formation, progression and treatment

BACKGROUND: Clinical and preclinical studies have revealed that alterations in DNA damage response (DDR) pathways may play an important role in prostate cancer (PCa) etiology and progression. These alterations can influence PCa responses to radiotherapy and anti-androgen treatment. The identificatio...

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Detalles Bibliográficos
Autores principales: Zhang, Wenhao, van Gent, Dik C., Incrocci, Luca, van Weerden, Wytske M., Nonnekens, Julie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8076026/
https://www.ncbi.nlm.nih.gov/pubmed/31197228
http://dx.doi.org/10.1038/s41391-019-0153-2