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Tumor suppression, dose-limiting toxicity and wellbeing with the fetal estrogen estetrol in patients with advanced breast cancer
PURPOSE: The aim of this study (the ABCE4 study) was to assess dose-limiting toxicity (DLT), safety, tolerability and preliminary efficacy of high doses of the fetal estrogen estetrol (E4) in postmenopausal patients with heavily pretreated, locally advanced and/or metastatic ER+/HER2−breast cancer,...
Autores principales: | Schmidt, Marcus, Lenhard, Hans, Hoenig, Arnd, Zimmerman, Yvette, Krijgh, Jan, Jansen, Monique, Coelingh Bennink, Herjan J. T. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8076125/ https://www.ncbi.nlm.nih.gov/pubmed/33242131 http://dx.doi.org/10.1007/s00432-020-03472-8 |
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