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Surveillance of respiratory syncytial virus infections in adults, Austria, 2017 to 2019

Respiratory syncytial virus (RSV) testing is generally available in most care centres, but it is rarely performed because clinicians’ seldom suspect RSV to be the underlying pathogen in adults with respiratory disease. Here, we evaluate the impact of broad combined influenza/RSV testing on the clini...

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Autores principales: Schubert, Lorenz, Steininger, Johanna, Lötsch, Felix, Herdina, Anna Nele, Redlberger-Fritz, Monika, Tobudic, Selma, Kundi, Michael, Strassl, Robert, Steininger, Christoph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8076173/
https://www.ncbi.nlm.nih.gov/pubmed/33903713
http://dx.doi.org/10.1038/s41598-021-88537-5
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author Schubert, Lorenz
Steininger, Johanna
Lötsch, Felix
Herdina, Anna Nele
Redlberger-Fritz, Monika
Tobudic, Selma
Kundi, Michael
Strassl, Robert
Steininger, Christoph
author_facet Schubert, Lorenz
Steininger, Johanna
Lötsch, Felix
Herdina, Anna Nele
Redlberger-Fritz, Monika
Tobudic, Selma
Kundi, Michael
Strassl, Robert
Steininger, Christoph
author_sort Schubert, Lorenz
collection PubMed
description Respiratory syncytial virus (RSV) testing is generally available in most care centres, but it is rarely performed because clinicians’ seldom suspect RSV to be the underlying pathogen in adults with respiratory disease. Here, we evaluate the impact of broad combined influenza/RSV testing on the clinical practice. Overall, 103 patients were tested positively for RSV. Our study indicates that positively tested patients were mostly of advanced age and suffered from chronic diseases. Mortality was significant in our cohort and higher in patients with advanced age. Further, we report a significant increase in detected RSV cases but also in detection rate. Together, these findings suggest that implementation of a combined influenza/RSV testing led to a significant increase in detection rate, supported clinicians establishing the correct diagnosis and allowed a safe and controlled handling of RSV patients.
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spelling pubmed-80761732021-04-27 Surveillance of respiratory syncytial virus infections in adults, Austria, 2017 to 2019 Schubert, Lorenz Steininger, Johanna Lötsch, Felix Herdina, Anna Nele Redlberger-Fritz, Monika Tobudic, Selma Kundi, Michael Strassl, Robert Steininger, Christoph Sci Rep Article Respiratory syncytial virus (RSV) testing is generally available in most care centres, but it is rarely performed because clinicians’ seldom suspect RSV to be the underlying pathogen in adults with respiratory disease. Here, we evaluate the impact of broad combined influenza/RSV testing on the clinical practice. Overall, 103 patients were tested positively for RSV. Our study indicates that positively tested patients were mostly of advanced age and suffered from chronic diseases. Mortality was significant in our cohort and higher in patients with advanced age. Further, we report a significant increase in detected RSV cases but also in detection rate. Together, these findings suggest that implementation of a combined influenza/RSV testing led to a significant increase in detection rate, supported clinicians establishing the correct diagnosis and allowed a safe and controlled handling of RSV patients. Nature Publishing Group UK 2021-04-26 /pmc/articles/PMC8076173/ /pubmed/33903713 http://dx.doi.org/10.1038/s41598-021-88537-5 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Schubert, Lorenz
Steininger, Johanna
Lötsch, Felix
Herdina, Anna Nele
Redlberger-Fritz, Monika
Tobudic, Selma
Kundi, Michael
Strassl, Robert
Steininger, Christoph
Surveillance of respiratory syncytial virus infections in adults, Austria, 2017 to 2019
title Surveillance of respiratory syncytial virus infections in adults, Austria, 2017 to 2019
title_full Surveillance of respiratory syncytial virus infections in adults, Austria, 2017 to 2019
title_fullStr Surveillance of respiratory syncytial virus infections in adults, Austria, 2017 to 2019
title_full_unstemmed Surveillance of respiratory syncytial virus infections in adults, Austria, 2017 to 2019
title_short Surveillance of respiratory syncytial virus infections in adults, Austria, 2017 to 2019
title_sort surveillance of respiratory syncytial virus infections in adults, austria, 2017 to 2019
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8076173/
https://www.ncbi.nlm.nih.gov/pubmed/33903713
http://dx.doi.org/10.1038/s41598-021-88537-5
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