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Functional modulation of phosphodiesterase-6 by calcium in mouse rod photoreceptors

Phosphodiesterase-6 (PDE6) is a key protein in the G-protein cascade converting photon information to bioelectrical signals in vertebrate photoreceptor cells. Here, we demonstrate that PDE6 is regulated by calcium, contrary to the common view that PDE1 is the unique PDE class whose activity is modul...

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Detalles Bibliográficos
Autores principales: Turunen, Teemu, Koskelainen, Ari
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8076185/
https://www.ncbi.nlm.nih.gov/pubmed/33903621
http://dx.doi.org/10.1038/s41598-021-88140-8

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