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PXDN reduces autophagic flux in insulin-resistant cardiomyocytes via modulating FoxO1

Autophagy, a well-observed intracellular lysosomal degradation process, is particularly important to the cell viability in diabetic cardiomyopathy (DCM). Peroxidasin (PXDN) is a heme-containing peroxidase that augments oxidative stress and plays an essential role in cardiovascular diseases, while wh...

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Detalles Bibliográficos
Autores principales:	Li, Chan, Liu, Zhaoya, Xu, Qian, Peng, Huihui, Cao, Jing, Zhou, Honghua, Zhang, Guogang, Cheng, Guangjie, Shi, Ruizheng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8076187/ https://www.ncbi.nlm.nih.gov/pubmed/33903591 http://dx.doi.org/10.1038/s41419-021-03699-4

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