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Prognostic significance of interleukin-17A-producing colorectal tumour antigen-specific T cells

BACKGROUND: The T cell cytokine profile is a key prognostic indicator of post-surgical outcome for colorectal cancer (CRC). Whilst T(H)1 (IFN-γ(+)) cell-mediated responses generated in CRC are well documented and are associated with improved survival, antigen-specific T(H)17 (IL-17A(+)) responses ha...

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Detalles Bibliográficos
Autores principales:	Thomson, Amanda, Bento, Diana F. Costa, Scurr, Martin J., Smart, Kathryn, Somerville, Michelle S., Keita, Åsa V., Gallimore, Awen, Godkin, Andrew
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8076199/ https://www.ncbi.nlm.nih.gov/pubmed/33674735 http://dx.doi.org/10.1038/s41416-021-01283-3

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