PAX8 and MECOM are interaction partners driving ovarian cancer

The transcription factor PAX8 is critical for the development of the thyroid and urogenital system. Comprehensive genomic screens furthermore indicate an additional oncogenic role for PAX8 in renal and ovarian cancers. While a plethora of PAX8-regulated genes in different contexts have been proposed...

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Autores principales: Bleu, Melusine, Mermet-Meillon, Fanny, Apfel, Verena, Barys, Louise, Holzer, Laura, Bachmann Salvy, Marianne, Lopes, Rui, Amorim Monteiro Barbosa, Inês, Delmas, Cecile, Hinniger, Alexandra, Chau, Suzanne, Kaufmann, Markus, Haenni, Simon, Berneiser, Karolin, Wahle, Maria, Moravec, Ivana, Vissières, Alexandra, Poetsch, Tania, Ahrné, Erik, Carte, Nathalie, Voshol, Johannes, Bechter, Elisabeth, Hamon, Jacques, Meyerhofer, Marco, Erdmann, Dirk, Fischer, Matteo, Stachyra, Therese, Freuler, Felix, Gutmann, Sascha, Fernández, César, Schmelzle, Tobias, Naumann, Ulrike, Roma, Guglielmo, Lawrenson, Kate, Nieto-Oberhuber, Cristina, Cobos-Correa, Amanda, Ferretti, Stephane, Schübeler, Dirk, Galli, Giorgio Giacomo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8076227/
https://www.ncbi.nlm.nih.gov/pubmed/33903593
http://dx.doi.org/10.1038/s41467-021-22708-w

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