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Aqueous and pH dependent coacervation method for taste masking of paracetamol via amorphous solid dispersion formation

Taste masking of paracetamol was achieved by preparing amorphous solid dispersion (ASD) using modified coacervation method. The method is based on dissolving the drug and polymeric carrier in water adjusted to certain pH level. Then, precipitation of ASD granules is performed by gradually changing p...

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Detalles Bibliográficos
Autores principales: Al-kasmi, Basheer, Alsirawan, M. H. D. Bashir, Paradkar, Anant, Nattouf, Abdul-Hakim, El-Zein, Hind
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8076289/
https://www.ncbi.nlm.nih.gov/pubmed/33903654
http://dx.doi.org/10.1038/s41598-021-88312-6

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