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A novel cystathionine γ-lyase inhibitor, I194496, inhibits the growth and metastasis of human TNBC via downregulating multiple signaling pathways

Triple-negative breast cancer (TNBC) is a high-risk subtype of breast cancer with high capacity for metastasis and lacking of therapeutic targets. Our previous studies indicated that cystathionine γ-lyase (CSE) may be a new target related to the recurrence or metastasis of TNBC. Downregulation of CS...

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Detalles Bibliográficos
Autores principales: Liu, Ya, Wang, Lupeng, Zhang, Xiuli, Deng, Yuying, Pan, Limin, Li, Hui, Shi, Xiaoyan, Wang, Tianxiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8076300/
https://www.ncbi.nlm.nih.gov/pubmed/33903672
http://dx.doi.org/10.1038/s41598-021-88355-9