Cargando…

Personal Neoantigens From Patients With NSCLC Induce Efficient Antitumor Responses

OBJECTIVE: To develop a neoantigen-targeted personalized cancer treatment for non-small cell lung cancer (NSCLC), neoantigens were obtained from collected human lung cancer samples, and the utility of neoantigen and neoantigen-reactive T cells (NRTs) was assessed. METHODS: Tumor specimens from three...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhang, Wei, Yin, Qi, Huang, Haidong, Lu, Jingjing, Qin, Hao, Chen, Si, Zhang, Wenjun, Su, Xiaoping, Sun, Weihong, Dong, Yuchao, Li, Qiang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8076796/ https://www.ncbi.nlm.nih.gov/pubmed/33928024 http://dx.doi.org/10.3389/fonc.2021.628456

Ejemplares similares

Personalized Neoantigen-Pulsed DC Vaccines: Advances in Clinical Applications
por: Tang, Lin, et al.
Publicado: (2021)

Artificial intelligence applied in neoantigen identification facilitates personalized cancer immunotherapy
por: Cai, Yu, et al.
Publicado: (2023)

The Clinical Application of Neoantigens in Esophageal Cancer
por: Gu, Yi-Min, et al.
Publicado: (2021)

Antitumor effect of neoantigen-reactive T cells combined with PD1 inhibitor therapy in mouse lung cancer
por: Qin, Huan, et al.
Publicado: (2023)

Systematically Characterizing A-to-I RNA Editing Neoantigens in Cancer
por: Zhou, Chi, et al.
Publicado: (2020)

The Role of Neoantigens in Cancer Immunotherapy
por: Zhu, Yueting, et al.
Publicado: (2021)

The Ways of Isolating Neoantigen-Specific T Cells
por: Li, Qing, et al.
Publicado: (2020)

A Potent Micron Neoantigen Tumor Vaccine GP‐Neoantigen Induces Robust Antitumor Activity in Multiple Tumor Models
por: Jing, Zhe, et al.
Publicado: (2022)

A Comprehensive Survey of Genomic Mutations in Breast Cancer Reveals Recurrent Neoantigens as Potential Therapeutic Targets
por: Zhou, Si, et al.
Publicado: (2022)

Cancer Neoantigens: Challenges and Future Directions for Prediction, Prioritization, and Validation
por: Borden, Elizabeth S., et al.
Publicado: (2022)

Personalized cancer neoantigen vaccines come of age
por: Chu, Yanhong, et al.
Publicado: (2018)

Mechanisms of Neoantigen-Targeted Induction of Pyroptosis and Ferroptosis: From Basic Research to Clinical Applications
por: Yu, Jie, et al.
Publicado: (2021)

Personalized neoantigen-based immunotherapy for advanced collecting duct carcinoma: case report
por: Zeng, Yongyi, et al.
Publicado: (2020)

Economic Impact of Tissue Testing and Treatments of Metastatic NSCLC in the Era of Personalized Medicine
por: Graham, Donna M., et al.
Publicado: (2014)

Hepatobiliary Tumor Organoids Reveal HLA Class I Neoantigen Landscape and Antitumoral Activity of Neoantigen Peptide Enhanced with Immune Checkpoint Inhibitors
por: Wang, Wenwen, et al.
Publicado: (2022)

SRC and MEK Co-inhibition Synergistically Enhances the Anti-tumor Effect in Both Non-small-cell Lung Cancer (NSCLC) and Erlotinib-Resistant NSCLC
por: Yuan, Man, et al.
Publicado: (2019)

Engineering neoantigen vaccines to improve cancer personalized immunotherapy
por: Liu, Zaoqu, et al.
Publicado: (2022)

ASNEO: Identification of personalized alternative splicing based neoantigens with RNA-seq
por: Zhang, Zhanbing, et al.
Publicado: (2020)

Comparison of Efficacy and Safety Between Immunotherapy and Docetaxel Monotherapy in NSCLC Patients
por: Yang, Wenchao, et al.
Publicado: (2022)

Spleen‐targeted neoantigen DNA vaccine for personalized immunotherapy of hepatocellular carcinoma
por: Wu, Ming, et al.
Publicado: (2023)

Personalized neoantigen-pulsed dendritic cell vaccines show superior immunogenicity to neoantigen-adjuvant vaccines in mouse tumor models
por: Zhang, Rui, et al.
Publicado: (2019)

Personal neoantigen cancer vaccines: The momentum builds
por: Fritsch, Edward F, et al.
Publicado: (2014)

Neoantigen Vaccine Delivery for Personalized Anticancer Immunotherapy
por: Guo, Yugang, et al.
Publicado: (2018)

Personalized neoantigen pulsed dendritic cell vaccine for advanced lung cancer
por: Ding, Zhenyu, et al.
Publicado: (2021)

Personalized neoantigen vaccine prevents postoperative recurrence in hepatocellular carcinoma patients with vascular invasion
por: Cai, Zhixiong, et al.
Publicado: (2021)

Immunotherapy and Targeting the Tumor Microenvironment: Current Place and New Insights in Primary Pulmonary NUT Carcinoma
por: Li, Xiang, et al.
Publicado: (2021)

Beyond Tumor Mutation Burden: Tumor Neoantigen Burden as a Biomarker for Immunotherapy and Other Types of Therapy
por: Wang, Peipei, et al.
Publicado: (2021)

Neoantigen-reactive T cells exhibit effective anti-tumor activity against colorectal cancer
por: Yu, Yaojun, et al.
Publicado: (2021)

Case Report: Pathological Complete Response in a Lung Metastasis of Phyllodes Tumor Patient Following Treatment Containing Peptide Neoantigen Nano-Vaccine
por: Sha, Huizi, et al.
Publicado: (2022)

Characterization of genomic alterations and neoantigens and analysis of immune infiltration identified therapeutic and prognostic biomarkers in adenocarcinoma at the gastroesophageal junction
por: Lao, Yueqiong, et al.
Publicado: (2022)

Neoantigen landscape in metastatic nasopharyngeal carcinoma
por: Lin, Mei, et al.
Publicado: (2021)

Current status and challenges of immunotherapy in ALK rearranged NSCLC
por: Qi, Rongbin, et al.
Publicado: (2022)

Microenvironment and the progress of immunotherapy in clinical practice of NSCLC brain metastasis
por: Xie, Mengqing, et al.
Publicado: (2023)

Immunopharmacogenomics towards personalized cancer immunotherapy targeting neoantigens
por: Kiyotani, Kazuma, et al.
Publicado: (2018)

Adoptive neoantigen-reactive T cell therapy: improvement strategies and current clinical researches
por: Huang, Ruichen, et al.
Publicado: (2023)

Neoantigen: A New Breakthrough in Tumor Immunotherapy
por: Zhang, Zheying, et al.
Publicado: (2021)

m(6)A regulators featured by tumor immune microenvironment landscapes and correlated with immunotherapy in non-small cell lung cancer (NSCLC)
por: Yuan, Baowen, et al.
Publicado: (2022)

INTEGRATE-neo: a pipeline for personalized gene fusion neoantigen discovery
por: Zhang, Jin, et al.
Publicado: (2017)

RB1 aberrations predict outcomes of immune checkpoint inhibitor combination therapy in NSCLC
por: Wang, Qian, et al.
Publicado: (2023)

The Landscape of Immunotherapy Resistance in NSCLC
por: Frisone, Daniele, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_19e5jr4nkn0mvpmd4mt1h3d1p9