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Fasudil Dichloroacetate Alleviates SU5416/Hypoxia-Induced Pulmonary Arterial Hypertension by Ameliorating Dysfunction of Pulmonary Arterial Smooth Muscle Cells

BACKGROUND: Pulmonary arterial hypertension (PAH) is an incurable disease that urgently needs therapeutic approaches. Based on the therapeutic effects of fasudil and dichloroacetate (DCA) on PAH, we aimed to explore the effects and potential mechanism of a new salt, fasudil dichloroacetate (FDCA), i...

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Detalles Bibliográficos
Autores principales:	Liu, Ping, Huang, Wen, Ding, Yirui, Wu, Jianbing, Liang, Zhuangzhuang, Huang, Zhangjian, Xie, Weiping, Kong, Hui
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2021
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8076841/ https://www.ncbi.nlm.nih.gov/pubmed/33935492 http://dx.doi.org/10.2147/DDDT.S297500

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