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A multi-targeting drug design strategy for identifying potent anti-SARS-CoV-2 inhibitors
The COVID-19, caused by SARS-CoV-2, is threatening public health, and there is no effective treatment. In this study, we have implemented a multi-targeted anti-viral drug design strategy to discover highly potent SARS-CoV-2 inhibitors, which simultaneously act on the host ribosome, viral RNA as well...
Autores principales: | Ren, Peng-xuan, Shang, Wei-juan, Yin, Wan-chao, Ge, Huan, Wang, Lin, Zhang, Xiang-lei, Li, Bing-qian, Li, Hong-lin, Xu, Ye-chun, Xu, Eric H., Jiang, Hua-liang, Zhu, Li-li, Zhang, Lei-ke, Bai, Fang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Singapore
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8076879/ https://www.ncbi.nlm.nih.gov/pubmed/33907306 http://dx.doi.org/10.1038/s41401-021-00668-7 |
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