Exploring the GLP-1–GLP-1R axis in porcine pancreas and gastrointestinal tract in vivo by ex vivo autoradiography

INTRODUCTION: Glucagon-like peptide-1 (GLP-1) increases insulin secretion from pancreatic beta-cells and GLP-1 receptor (GLP-1R) agonists are widely used as treatment for type 2 diabetes mellitus. Studying occupancy of the GLP-1R in various tissues is challenging due to lack of quantitative, repeata...

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Detalles Bibliográficos
Autores principales: Manell, Elin, Puuvuori, Emmi, Svensson, Anna, Velikyan, Irina, Hulsart-Billström, Gry, Hedenqvist, Patricia, Holst, Jens Juul, Jensen Waern, Marianne, Eriksson, Olof
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2021
Materias:
Metabolism
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8076945/
https://www.ncbi.nlm.nih.gov/pubmed/33903116
http://dx.doi.org/10.1136/bmjdrc-2020-002083

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8076945/
https://www.ncbi.nlm.nih.gov/pubmed/33903116
http://dx.doi.org/10.1136/bmjdrc-2020-002083

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