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Neuroprotective Effects of Oxymatrine on PI3K/Akt/mTOR Pathway After Hypoxic-Ischemic Brain Damage in Neonatal Rats
Oxymatrine (OMT), a quinolizidine alkaloid extracted from traditional Chinese herb Sophora flavescens Ait, has drawn attention because of its beneficial bioactivities against hypoxic–ischemic brain damage (HIBD). However, the underlying molecular mechanism remains unclear. In this study, we determin...
Autores principales: | Wei, Wei, Lu, Min, Lan, Xiao-bing, Liu, Ning, Su, Wei-ke, Dushkin, Alexandr V., Yu, Jian-qiang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8077028/ https://www.ncbi.nlm.nih.gov/pubmed/33927621 http://dx.doi.org/10.3389/fphar.2021.642415 |
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