An unusual case of chronic lymphocytic leukemia with trisomy 12 presenting with prolymphocytic transformation and t(8;21)(q22;q22)

First report of t(8;21)(q22;q22) in a patient with CLL. RUNX1‐RUNX1T1 fusion gene resulting from the translocation may have played a role in the prolymphocytic transformation.

Detalles Bibliográficos
Autores principales: Bhushan, Mishi, Kumar, Kirthi R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Clinical Images
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8077250/
https://www.ncbi.nlm.nih.gov/pubmed/33936733
http://dx.doi.org/10.1002/ccr3.4059
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author Bhushan, Mishi
Kumar, Kirthi R.
author_facet Bhushan, Mishi
Kumar, Kirthi R.
author_sort Bhushan, Mishi
collection PubMed
description First report of t(8;21)(q22;q22) in a patient with CLL. RUNX1‐RUNX1T1 fusion gene resulting from the translocation may have played a role in the prolymphocytic transformation.
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spelling pubmed-80772502021-04-29 An unusual case of chronic lymphocytic leukemia with trisomy 12 presenting with prolymphocytic transformation and t(8;21)(q22;q22) Bhushan, Mishi Kumar, Kirthi R. Clin Case Rep Clinical Images First report of t(8;21)(q22;q22) in a patient with CLL. RUNX1‐RUNX1T1 fusion gene resulting from the translocation may have played a role in the prolymphocytic transformation. John Wiley and Sons Inc. 2021-03-15 /pmc/articles/PMC8077250/ /pubmed/33936733 http://dx.doi.org/10.1002/ccr3.4059 Text en © 2021 The Authors. Clinical Case Reports published by John Wiley & Sons Ltd. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Clinical Images
Bhushan, Mishi
Kumar, Kirthi R.
An unusual case of chronic lymphocytic leukemia with trisomy 12 presenting with prolymphocytic transformation and t(8;21)(q22;q22)
title An unusual case of chronic lymphocytic leukemia with trisomy 12 presenting with prolymphocytic transformation and t(8;21)(q22;q22)
title_full An unusual case of chronic lymphocytic leukemia with trisomy 12 presenting with prolymphocytic transformation and t(8;21)(q22;q22)
title_fullStr An unusual case of chronic lymphocytic leukemia with trisomy 12 presenting with prolymphocytic transformation and t(8;21)(q22;q22)
title_full_unstemmed An unusual case of chronic lymphocytic leukemia with trisomy 12 presenting with prolymphocytic transformation and t(8;21)(q22;q22)
title_short An unusual case of chronic lymphocytic leukemia with trisomy 12 presenting with prolymphocytic transformation and t(8;21)(q22;q22)
title_sort unusual case of chronic lymphocytic leukemia with trisomy 12 presenting with prolymphocytic transformation and t(8;21)(q22;q22)
topic Clinical Images
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8077250/
https://www.ncbi.nlm.nih.gov/pubmed/33936733
http://dx.doi.org/10.1002/ccr3.4059
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