BRAF‐mutated malignant melanoma with chondrosarcomatous differentiation in inguinal nodal metastasis

We report the case of a young woman who developed metastatic melanoma in the inguinal nodal region, which acquired chondrosarcomatous differentiation and preserved the BRAF mutation found in the primary tumor. The patient was treated with a BRAF/MEK inhibitor combination therapy (dabrafenib/trametin...

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Detalles Bibliográficos
Autores principales: Abbati, Francesca, Altimari, Annalisa, Corti, Barbara, Dika, Emi, Sperandi, Francesca, Melotti, Barbara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Case Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8077358/
https://www.ncbi.nlm.nih.gov/pubmed/33936664
http://dx.doi.org/10.1002/ccr3.3982
Descripción
Sumario:We report the case of a young woman who developed metastatic melanoma in the inguinal nodal region, which acquired chondrosarcomatous differentiation and preserved the BRAF mutation found in the primary tumor. The patient was treated with a BRAF/MEK inhibitor combination therapy (dabrafenib/trametinib), which was demonstrated to be effective and well‐tolerated.

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