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Clonal Upregulation of Effector Cytotoxic T Lymphocytes in a Patient with Multiple Tyrosine Kinase Inhibitor-Refractory Chronic Myeloid Leukemia with Long-Term Survival
We present the case of a patient with multiple tyrosine kinase inhibitor (TKI)-refractory chronic phase chronic myeloid leukemia (CP-CML) with a T315I mutation of abl1. Dasatinib, a second-generation TKI, was administered as the initial treatment but achieved neither a cytogenetic nor molecular resp...
Autores principales: | Jo, Tatsuro, Sakai, Takahiro, Matsuzaka, Kaori, Noguchi, Kazuhiro, Hayashi, Shizuka, Matsuo, Masatoshi, Taguchi, Jun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
S. Karger AG
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8077377/ https://www.ncbi.nlm.nih.gov/pubmed/33976626 http://dx.doi.org/10.1159/000514631 |
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