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Myosin-X is dispensable for spindle morphogenesis and positioning in the mouse oocyte

Off-center spindle positioning in mammalian oocytes enables asymmetric divisions in size, which are important for subsequent embryogenesis. The migration of the meiosis I spindle from the oocyte center to its cortex is mediated by F-actin. Specifically, an F-actin cage surrounds the microtubule spin...

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Detalles Bibliográficos
Autores principales: Crozet, Flora, Da Silva, Christelle, Verlhac, Marie-Hélène, Terret, Marie-Emilie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8077531/
https://www.ncbi.nlm.nih.gov/pubmed/33722900
http://dx.doi.org/10.1242/dev.199364