A Rare Case of Thyroid Carcinoma Showing Thymus-Like Differentiation in a Young Adult

Thyroid carcinoma showing thymus-like differentiation (CASTLE) is thought to originate from ectopic thymic tissue or remnants of the developing thymus within or adjacent to the thyroid. This case report describes a mass located on the left thyroid of a 28-year-old man. Fine-needle aspiration cytolog...

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Detalles Bibliográficos
Autores principales: Kimura, Eri, Enomoto, Keisuke, Kono, Masamitsu, Tamagawa, Shunji, Takeda, Saori, Kumashiro, Naoko, Hirayama, Shun, Kimura, Takahito, Hotomi, Muneki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2021
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8077592/
https://www.ncbi.nlm.nih.gov/pubmed/33976651
http://dx.doi.org/10.1159/000514271
Descripción
Sumario:Thyroid carcinoma showing thymus-like differentiation (CASTLE) is thought to originate from ectopic thymic tissue or remnants of the developing thymus within or adjacent to the thyroid. This case report describes a mass located on the left thyroid of a 28-year-old man. Fine-needle aspiration cytology revealed a number of lymphoid cells without atypia that were similar to those seen in a malignant lymphoma of the thyroid, and surgery was performed. Based on additional histopathological findings, the tumor was finally diagnosed as a CASTLE. It is difficult to diagnose this neoplasm using fine-needle aspiration cytology. However, it is possible to differentially diagnose CASTLE based on its histological features. CD5 is useful for diagnosing CASTLE with immunohistochemical staining.

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