Manganese/bipyridine-catalyzed non-directed C(sp(3))–H bromination using NBS and TMSN(3)

A Mn(II)/bipyridine-catalyzed bromination reaction of unactivated aliphatic C(sp(3))−H bonds has been developed using N-bromosuccinimide (NBS) as the brominating reagent. The reaction proceeded in moderate-to-good yield, even on a gram scale. The introduced bromine atom can be converted into fluorin...

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Detalles Bibliográficos
Autores principales: Sneh, Kumar, Torigoe, Takeru, Kuninobu, Yoichiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2021
Materias:
Letter
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8077618/
https://www.ncbi.nlm.nih.gov/pubmed/33968261
http://dx.doi.org/10.3762/bjoc.17.74
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author Sneh, Kumar
Torigoe, Takeru
Kuninobu, Yoichiro
author_facet Sneh, Kumar
Torigoe, Takeru
Kuninobu, Yoichiro
author_sort Sneh, Kumar
collection PubMed
description A Mn(II)/bipyridine-catalyzed bromination reaction of unactivated aliphatic C(sp(3))−H bonds has been developed using N-bromosuccinimide (NBS) as the brominating reagent. The reaction proceeded in moderate-to-good yield, even on a gram scale. The introduced bromine atom can be converted into fluorine and allyl groups.
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spelling pubmed-80776182021-05-06 Manganese/bipyridine-catalyzed non-directed C(sp(3))–H bromination using NBS and TMSN(3) Sneh, Kumar Torigoe, Takeru Kuninobu, Yoichiro Beilstein J Org Chem Letter A Mn(II)/bipyridine-catalyzed bromination reaction of unactivated aliphatic C(sp(3))−H bonds has been developed using N-bromosuccinimide (NBS) as the brominating reagent. The reaction proceeded in moderate-to-good yield, even on a gram scale. The introduced bromine atom can be converted into fluorine and allyl groups. Beilstein-Institut 2021-04-22 /pmc/articles/PMC8077618/ /pubmed/33968261 http://dx.doi.org/10.3762/bjoc.17.74 Text en Copyright © 2021, Sneh et al. https://creativecommons.org/licenses/by/4.0/https://www.beilstein-journals.org/bjoc/terms/termsThis is an Open Access article under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0 (https://creativecommons.org/licenses/by/4.0/) ). Please note that the reuse, redistribution and reproduction in particular requires that the author(s) and source are credited and that individual graphics may be subject to special legal provisions. The license is subject to the Beilstein Journal of Organic Chemistry terms and conditions: (https://www.beilstein-journals.org/bjoc/terms/terms)
spellingShingle Letter
Sneh, Kumar
Torigoe, Takeru
Kuninobu, Yoichiro
Manganese/bipyridine-catalyzed non-directed C(sp(3))–H bromination using NBS and TMSN(3)
title Manganese/bipyridine-catalyzed non-directed C(sp(3))–H bromination using NBS and TMSN(3)
title_full Manganese/bipyridine-catalyzed non-directed C(sp(3))–H bromination using NBS and TMSN(3)
title_fullStr Manganese/bipyridine-catalyzed non-directed C(sp(3))–H bromination using NBS and TMSN(3)
title_full_unstemmed Manganese/bipyridine-catalyzed non-directed C(sp(3))–H bromination using NBS and TMSN(3)
title_short Manganese/bipyridine-catalyzed non-directed C(sp(3))–H bromination using NBS and TMSN(3)
title_sort manganese/bipyridine-catalyzed non-directed c(sp(3))–h bromination using nbs and tmsn(3)
topic Letter
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8077618/
https://www.ncbi.nlm.nih.gov/pubmed/33968261
http://dx.doi.org/10.3762/bjoc.17.74
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AT torigoetakeru manganesebipyridinecatalyzednondirectedcsp3hbrominationusingnbsandtmsn3
AT kuninobuyoichiro manganesebipyridinecatalyzednondirectedcsp3hbrominationusingnbsandtmsn3

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