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Small ring has big potential: insights into extrachromosomal DNA in cancer

Recent technical advances have led to the discovery of novel functions of extrachromosomal DNA (ecDNA) in multiple cancer types. Studies have revealed that cancer-associated ecDNA shows a unique circular shape and contains oncogenes that are more frequently amplified than that in linear chromatin DN...

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Detalles Bibliográficos
Autores principales: Wang, Yihao, Huang, Rui, Zheng, Guopei, Shen, Jianfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8077740/
https://www.ncbi.nlm.nih.gov/pubmed/33902601
http://dx.doi.org/10.1186/s12935-021-01936-6

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