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CB1 receptor antagonist rimonabant protects against chronic intermittent hypoxia-induced renal injury in rats

BACKGROUND: Obstructive sleep apnoea (OSA) induced chronic kidney disease is mainly caused by chronic intermittent hypoxia (CIH). Our study investigate the mechanism underlying CIH-induced renal damage and whether the cannabinoid receptor 1 (CB1R) antagonist rimonabant (Ri) alleviates CIH-induced re...

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Detalles Bibliográficos
Autores principales: Zhao, Li, Liu, Tao, Dou, Zhan-jun, Wang, Mei-ting, Hu, Zi-xuan, Wang, Bei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8077827/
https://www.ncbi.nlm.nih.gov/pubmed/33902473
http://dx.doi.org/10.1186/s12882-021-02362-6