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Small molecule inhibitors against PD-1/PD-L1 immune checkpoints and current methodologies for their development: a review

Programmed death-1/programmed death ligand-1 (PD-1/PD-L1) based immunotherapy is a revolutionary cancer therapy with great clinical success. The majority of clinically used PD-1/PD-L1 inhibitors are monoclonal antibodies but their applications are limited due to their poor oral bioavailability and i...

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Detalles Bibliográficos
Autores principales:	Liu, Chang, Seeram, Navindra P., Ma, Hang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8077906/ https://www.ncbi.nlm.nih.gov/pubmed/33906641 http://dx.doi.org/10.1186/s12935-021-01946-4

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