Cargando…

Whole-genome sequencing of phenotypically distinct inflammatory breast cancers reveals similar genomic alterations to non-inflammatory breast cancers

BACKGROUND: Inflammatory breast cancer (IBC) has a highly invasive and metastatic phenotype. However, little is known about its genetic drivers. To address this, we report the largest cohort of whole-genome sequencing (WGS) of IBC cases. METHODS: We performed WGS of 20 IBC samples and paired normal...

Descripción completa

Detalles Bibliográficos
Autores principales:	Li, Xiaotong, Kumar, Sushant, Harmanci, Arif, Li, Shantao, Kitchen, Robert R., Zhang, Yan, Wali, Vikram B., Reddy, Sangeetha M., Woodward, Wendy A., Reuben, James M., Rozowsky, Joel, Hatzis, Christos, Ueno, Naoto T., Krishnamurthy, Savitri, Pusztai, Lajos, Gerstein, Mark
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8077918/ https://www.ncbi.nlm.nih.gov/pubmed/33902690 http://dx.doi.org/10.1186/s13073-021-00879-x

Ejemplares similares

Comparison of molecular subtype distribution in triple-negative inflammatory and non-inflammatory breast cancers
por: Masuda, Hiroko, et al.
Publicado: (2013)

Predictors of Chemosensitivity in Triple Negative Breast Cancer: An Integrated Genomic Analysis
por: Jiang, Tingting, et al.
Publicado: (2016)

Genomic and Immune Profiling of a Patient With Triple-Negative Breast Cancer That Progressed During Neoadjuvant Chemotherapy Plus PD-L1 Blockade
por: Casadevall, David, et al.
Publicado: (2019)

Statistical measures of transcriptional diversity capture genomic heterogeneity of cancer
por: Jiang, Tingting, et al.
Publicado: (2014)

The impact of Ki-67 in the context of multidisciplinary care in primary inflammatory breast cancer
por: Ning, Jing, et al.
Publicado: (2019)

Decorin-mediated suppression of tumorigenesis, invasion, and metastasis in inflammatory breast cancer
por: Hu, Xiaoding, et al.
Publicado: (2021)

Status of the anaplastic lymphoma kinase (ALK) gene in inflammatory breast carcinoma
por: Krishnamurthy, Savitri, et al.
Publicado: (2013)

Identification and Validation of a Novel Biologics Target in Triple Negative Breast Cancer
por: Wali, Vikram B., et al.
Publicado: (2019)

Characterization of DNA variants in the human kinome in breast cancer
por: Agarwal, Divyansh, et al.
Publicado: (2015)

A genome-wide approach to link genotype to clinical outcome by utilizing next generation sequencing and gene chip data of 6,697 breast cancer patients
por: Pongor, Lőrinc, et al.
Publicado: (2015)

Scientific Summary from the Morgan Welch MD Anderson Cancer Center Inflammatory Breast Cancer (IBC) Program 10(th) Anniversary Conference
por: Woodward, Wendy A., et al.
Publicado: (2017)

Reliability of Whole-Exome Sequencing for Assessing Intratumor Genetic Heterogeneity
por: Shi, Weiwei, et al.
Publicado: (2018)

Multi-Omics Investigation of Innate Navitoclax Resistance in Triple-Negative Breast Cancer Cells
por: Marczyk, Michal, et al.
Publicado: (2020)

A uniform survey of allele-specific binding and expression over 1000-Genomes-Project individuals
por: Chen, Jieming, et al.
Publicado: (2016)

Mesenchymal stem cells mediate the clinical phenotype of inflammatory breast cancer in a preclinical model
por: Lacerda, Lara, et al.
Publicado: (2015)

Inflammation Mediated Metastasis: Immune Induced Epithelial-To-Mesenchymal Transition in Inflammatory Breast Cancer Cells
por: Cohen, Evan N., et al.
Publicado: (2015)

Immune profiling of pre- and post-treatment breast cancer tissues from the SWOG S0800 neoadjuvant trial
por: Li, Xiaotong, et al.
Publicado: (2019)

Treatment scheduling effects on the evolution of drug resistance in heterogeneous cancer cell populations
por: Patwardhan, Gauri A., et al.
Publicado: (2021)

Multigene prognostic tests in breast cancer: past, present, future
por: Győrffy, Balázs, et al.
Publicado: (2015)

MUSIC: identification of enriched regions in ChIP-Seq experiments using a mappability-corrected multiscale signal processing framework
por: Harmanci, Arif, et al.
Publicado: (2014)

Lipocalin 2 promotes inflammatory breast cancer tumorigenesis and skin invasion
por: Villodre, Emilly S., et al.
Publicado: (2021)

Validation of Prognostic Stage and Anatomic Stage in the American Joint Committee on Cancer 8th Edition for Inflammatory Breast Cancer
por: Kida, Kumiko, et al.
Publicado: (2020)

An integrative bioinformatics approach reveals coding and non-coding gene variants associated with gene expression profiles and outcome in breast cancer molecular subtypes
por: Győrffy, Balázs, et al.
Publicado: (2018)

Inflammatory breast cancer biomarker identification by simultaneous TGIRT-seq profiling of coding and non-coding RNAs in tumors and blood
por: Wylie, Dennis, et al.
Publicado: (2023)

Understanding genome structural variations
por: Abyzov, Alexej, et al.
Publicado: (2015)

International Consensus on the Clinical Management of Inflammatory Breast Cancer from the Morgan Welch Inflammatory Breast Cancer Research Program 10th Anniversary Conference
por: Ueno, Naoto T., et al.
Publicado: (2018)

Distinct epidemiological profiles associated with inflammatory breast cancer (IBC): A comprehensive analysis of the IBC registry at The University of Texas MD Anderson Cancer Center
por: Fouad, Tamer M., et al.
Publicado: (2018)

Quantitative hormone receptor (HR) expression and gene expression analysis in HR+ inflammatory breast cancer (IBC) vs non-IBC
por: Iwase, Toshiaki, et al.
Publicado: (2020)

Analysis of sensitive information leakage in functional genomics signal profiles through genomic deletions
por: Harmanci, Arif, et al.
Publicado: (2018)

Inflammatory Breast Cancer: A Distinct Clinicopathological Entity Transcending Histological Distinction
por: Raghav, K., et al.
Publicado: (2016)

Functional polymorphisms in cancer
por: Agarwal, Divyansh, et al.
Publicado: (2015)

Increased epigenetic age in normal breast tissue from luminal breast cancer patients
por: Hofstatter, Erin W., et al.
Publicado: (2018)

A target of potential RELAvance in inflammatory breast cancer
por: Eckhardt, Bedrich L., et al.
Publicado: (2017)

Circulating tumor cells in newly diagnosed inflammatory breast cancer
por: Mego, Michal, et al.
Publicado: (2015)

Gene expression profiling of breast cancer
por: Pusztai, Lajos
Publicado: (2009)

Cyclin E overexpression as a biomarker for combination treatment strategies in inflammatory breast cancer
por: Alexander, Angela, et al.
Publicado: (2017)

Ultrastructural Analysis of Inflammatory Breast Cancer Cell Clusters in an Ex Vivo Environment Mechanically Mimicking the Lymph Vascular System
por: Fujii, Yuka, et al.
Publicado: (2021)

Whole-genome analysis of papillary kidney cancer finds significant noncoding alterations
por: Li, Shantao, et al.
Publicado: (2017)

High Serum miR-19a Levels Are Associated with Inflammatory Breast Cancer and Are Predictive of Favorable Clinical Outcome in Patients with Metastatic HER2(+) Inflammatory Breast Cancer
por: Anfossi, Simone, et al.
Publicado: (2014)

NDRG1 Expression Is an Independent Prognostic Factor in Inflammatory Breast Cancer
por: Villodre, Emilly S., et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_vdvef2u7kmd61o8i705d5rog30