Therapeutic Efficacy of Lactonic Sophorolipids: Nanoceria-Assisted Combination Therapy of NSCLC using HDAC and Hsp90 Inhibitors

Purpose: Non-Small-Cell Lung Cancer (NSCLC) has gained resistance to common chemo- and radiotherapy due to the oncogenic K-RAS mutations. In this work, lactonic sophorolipids (LSL), a constituent of natural sophorolipids known to inhibit histone deacetylase (HDAC) activity, is used to evaluate its p...

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Detalles Bibliográficos
Autores principales: Naz, Shuguftha, Banerjee, Tuhina, Totsingan, Filbert, Woody, Kalee, Gross, Richard A., Santra, Santimukul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8077971/
https://www.ncbi.nlm.nih.gov/pubmed/33912379
http://dx.doi.org/10.7150/ntno.57675

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8077971/
https://www.ncbi.nlm.nih.gov/pubmed/33912379
http://dx.doi.org/10.7150/ntno.57675

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