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Association between vitamin D receptor polymorphisms and acute pancreatitis: A protocol for systematic review and meta analysis
BACKGROUND: Several studies have been performed to investigate the association between vitamin D receptor (VDR) gene polymorphism and acute pancreatitis, but the results are inconclusive. We conducted this meta-analysis for a precise estimation of the association between BsmI (rs1544410), ApaI (rs79...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Lippincott Williams & Wilkins
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8078433/ https://www.ncbi.nlm.nih.gov/pubmed/33879686 http://dx.doi.org/10.1097/MD.0000000000025508 |
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author | Li, Xiaofeng Gan, Xianghai Gong, Junzuo Mou, Tianyi Zhou, Hua Li, Mengqin |
author_facet | Li, Xiaofeng Gan, Xianghai Gong, Junzuo Mou, Tianyi Zhou, Hua Li, Mengqin |
author_sort | Li, Xiaofeng |
collection | PubMed |
description | BACKGROUND: Several studies have been performed to investigate the association between vitamin D receptor (VDR) gene polymorphism and acute pancreatitis, but the results are inconclusive. We conducted this meta-analysis for a precise estimation of the association between BsmI (rs1544410), ApaI (rs7975232), TaqI (rs731236), and FokI (rs2228570) polymorphisms and acute pancreatitis. METHODS: Appropriate studies were retrieved by searching Web of Science, PubMed, Scopus, and Google scholar databases, until January 31, 2021. Two reviewers independently conducted data extraction and literature quality evaluation. Odds ratios and 95% confidence intervals were calculated to evaluate the strength of the association. All of the data were analyzed with Stata 16.0. RESULTS: The results of this meta-analysis will be submitted to a peer-reviewed journal for publication. CONCLUSIONS: This meta-analysis will summarize the association between BsmI, ApaI, TaqI, and FokI polymorphisms and the risk of acute pancreatitis. ETHICS AND DISSEMINATION: Ethical approval was not required for this study. The systematic review will be published in a peer-reviewed journal, presented at conferences, and shared on social media platforms. OSF REGISTRATION NUMBER: DOI 10.17605/OSF.IO/83W7R. |
format | Online Article Text |
id | pubmed-8078433 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Lippincott Williams & Wilkins |
record_format | MEDLINE/PubMed |
spelling | pubmed-80784332021-04-28 Association between vitamin D receptor polymorphisms and acute pancreatitis: A protocol for systematic review and meta analysis Li, Xiaofeng Gan, Xianghai Gong, Junzuo Mou, Tianyi Zhou, Hua Li, Mengqin Medicine (Baltimore) 4500 BACKGROUND: Several studies have been performed to investigate the association between vitamin D receptor (VDR) gene polymorphism and acute pancreatitis, but the results are inconclusive. We conducted this meta-analysis for a precise estimation of the association between BsmI (rs1544410), ApaI (rs7975232), TaqI (rs731236), and FokI (rs2228570) polymorphisms and acute pancreatitis. METHODS: Appropriate studies were retrieved by searching Web of Science, PubMed, Scopus, and Google scholar databases, until January 31, 2021. Two reviewers independently conducted data extraction and literature quality evaluation. Odds ratios and 95% confidence intervals were calculated to evaluate the strength of the association. All of the data were analyzed with Stata 16.0. RESULTS: The results of this meta-analysis will be submitted to a peer-reviewed journal for publication. CONCLUSIONS: This meta-analysis will summarize the association between BsmI, ApaI, TaqI, and FokI polymorphisms and the risk of acute pancreatitis. ETHICS AND DISSEMINATION: Ethical approval was not required for this study. The systematic review will be published in a peer-reviewed journal, presented at conferences, and shared on social media platforms. OSF REGISTRATION NUMBER: DOI 10.17605/OSF.IO/83W7R. Lippincott Williams & Wilkins 2021-04-23 /pmc/articles/PMC8078433/ /pubmed/33879686 http://dx.doi.org/10.1097/MD.0000000000025508 Text en Copyright © 2021 the Author(s). Published by Wolters Kluwer Health, Inc. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License 4.0 (CCBY), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. http://creativecommons.org/licenses/by/4.0 (https://creativecommons.org/licenses/by/4.0/) |
spellingShingle | 4500 Li, Xiaofeng Gan, Xianghai Gong, Junzuo Mou, Tianyi Zhou, Hua Li, Mengqin Association between vitamin D receptor polymorphisms and acute pancreatitis: A protocol for systematic review and meta analysis |
title | Association between vitamin D receptor polymorphisms and acute pancreatitis: A protocol for systematic review and meta analysis |
title_full | Association between vitamin D receptor polymorphisms and acute pancreatitis: A protocol for systematic review and meta analysis |
title_fullStr | Association between vitamin D receptor polymorphisms and acute pancreatitis: A protocol for systematic review and meta analysis |
title_full_unstemmed | Association between vitamin D receptor polymorphisms and acute pancreatitis: A protocol for systematic review and meta analysis |
title_short | Association between vitamin D receptor polymorphisms and acute pancreatitis: A protocol for systematic review and meta analysis |
title_sort | association between vitamin d receptor polymorphisms and acute pancreatitis: a protocol for systematic review and meta analysis |
topic | 4500 |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8078433/ https://www.ncbi.nlm.nih.gov/pubmed/33879686 http://dx.doi.org/10.1097/MD.0000000000025508 |
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