Functional analyses of human LUC7-like proteins involved in splicing regulation and myeloid neoplasms

Vertebrates have evolved three paralogs, termed LUC7L, LUC7L2, and LUC7L3, of the essential yeast U1 small nuclear RNA (snRNA)-associated splicing factor Luc7p. We investigated the mechanistic and regulatory functions of these putative splicing factors, of which one (LUC7L2) is mutated or deleted in...

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Detalles Bibliográficos
Autores principales: Daniels, Noah J., Hershberger, Courtney E., Gu, Xiaorong, Schueger, Caroline, DiPasquale, William M., Brick, Jonathan, Saunthararajah, Yogen, Maciejewski, Jaroslaw P., Padgett, Richard A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8078730/
https://www.ncbi.nlm.nih.gov/pubmed/33852859
http://dx.doi.org/10.1016/j.celrep.2021.108989

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8078730/
https://www.ncbi.nlm.nih.gov/pubmed/33852859
http://dx.doi.org/10.1016/j.celrep.2021.108989

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