Cargando…

Nucleoporin TPR (translocated promoter region, nuclear basket protein) upregulation alters MTOR-HSF1 trails and suppresses autophagy induction in ependymoma

Children with ependymoma have high mortality rates because ependymoma is resistant to conventional therapy. Genomic and transcriptomic studies have identified potential targets as significantly altered genes in ependymoma patients. Although several candidate oncogenes in ependymoma were recently rep...

Descripción completa

Detalles Bibliográficos
Autores principales:	Dewi, Firli Rahmah Primula, Jiapaer, Shabierjiang, Kobayashi, Akiko, Hazawa, Masaharu, Ikliptikawati, Dini Kurnia, Hartono, Sabit, Hemragul, Nakada, Mitsutoshi, Wong, Richard W.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2020
Materias:	Brief Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8078762/ https://www.ncbi.nlm.nih.gov/pubmed/32207633 http://dx.doi.org/10.1080/15548627.2020.1741318

Ejemplares similares

Nucleoporin Nup58 localizes to centrosomes and mid-bodies during mitosis
por: Hartono, et al.
Publicado: (2019)

RBPJ contributes to the malignancy of glioblastoma and induction of proneural‐mesenchymal transition via IL‐6‐STAT3 pathway
por: Zhang, Guangtao, et al.
Publicado: (2020)

Regulation of autophagy by nucleoporin Tpr
por: Funasaka, Tatsuyoshi, et al.
Publicado: (2012)

Methylation impact analysis of erythropoietin (EPO) Gene to hypoxia inducible factor-1α (HIF-1α) activity
por: Dewi, Firli Rahmah Primula, et al.
Publicado: (2013)

CBMS-12 PENTAMIDINE; TRANSLATIONAL RESEARCH FOR A NEW CHEMOTHERAPY TARGETING ON GLIOMA CELLS AND GLIOMA STEM CELLS USING DRUG REPOSITIONING
por: Tamai, Sho, et al.
Publicado: (2019)

Therapeutic potential of pentamidine for glioma‐initiating cells and glioma cells through multimodal antitumor effects
por: Tamai, Sho, et al.
Publicado: (2023)

In Silico Interaction of the Active Compounds of Scurrula Atropurpurea with the RANK/RANKL/OPG System in Diabetoporosis
por: Akbar, Izaak Zoelkarnain, et al.
Publicado: (2019)

Colorectal cancer cells require glycogen synthase kinase-3β for sustaining mitosis via translocated promoter region (TPR)-dynein interaction
por: Dewi, Firli R.P., et al.
Publicado: (2018)

Gelsolin inhibits malignant phenotype of glioblastoma and is regulated by miR‐654‐5p and miR‐450b‐5p
por: Zhang, Jiakang, et al.
Publicado: (2020)

Localization of Nucleoporin Tpr to the Nuclear Pore Complex Is Essential for Tpr Mediated Regulation of the Export of Unspliced RNA
por: Rajanala, Kalpana, et al.
Publicado: (2012)

Regulation by Phloroglucinol of Nrf2/Maf-Mediated Expression of Antioxidant Enzymes and Inhibition of Osteoclastogenesis via the RANKL/RANK Signaling Pathway: In Silico study
por: Rahim, Agus Hadian, et al.
Publicado: (2015)

Increasing the effect of annonacin using nanodiamonds to inhibit breast cancer cells growth in rats (Rattus norvegicus)-Induced breast cancer
por: Dewi, Firli Rahmah Primula, et al.
Publicado: (2022)

Identification of antipsychotic drug fluspirilene as a potential anti-glioma stem cell drug
por: Dong, Yu, et al.
Publicado: (2017)

Identification of GSK3β inhibitor kenpaullone as a temozolomide enhancer against glioblastoma
por: Kitabayashi, Tomohiro, et al.
Publicado: (2019)

Overexpression of SARS-CoV-2 protein ORF6 dislocates RAE1 and NUP98 from the nuclear pore complex
por: Kato, Koki, et al.
Publicado: (2021)

Nucleoporin TPR is an integral component of the TREX-2 mRNA export pathway
por: Aksenova, Vasilisa, et al.
Publicado: (2020)

The human nucleoporin Tpr protects cells from RNA-mediated replication stress
por: Kosar, Martin, et al.
Publicado: (2021)

Cinnamomum burmanini Blume increases bone turnover marker and induces tibia's granule formation in ovariectomized rats
por: Kania, Nia, et al.
Publicado: (2018)

Nucleoporin TPR promotes tRNA nuclear export and protein synthesis in lung cancer cells
por: Chen, Miao, et al.
Publicado: (2021)

Potential Strategies Overcoming the Temozolomide Resistance for Glioblastoma
por: JIAPAER, Shabierjiang, et al.
Publicado: (2018)

The potential of A. Muricata Bioactive Compounds to Inhibit HIF1α Expression Via Disruption of Tyrosine Kinase Receptor Activity: an In Silico Study
por: Dewi, Firli Rahmah Primula, et al.
Publicado: (2021)

Higher Nucleoporin-Importinβ Affinity at the Nuclear Basket Increases Nucleocytoplasmic Import
por: Azimi, Mohammad, et al.
Publicado: (2013)

Anti-cancer activity of an ethanolic extract of red okra pods (Abelmoschus esculentus L. Moench) in rats induced by N-methyl-N-nitrosourea
por: Pramudya, Manikya, et al.
Publicado: (2022)

Effect of the Ethanol Extract of Red Okra Pods (Abelmoschus esculentus (L.) Moench) to Inhibit Cervical Cancer Cells Growth through Cell Cycle-Associated Oncogenes
por: Nisa, Nabilatun, et al.
Publicado: (2022)

Nucleoporin 153 Arrests the Nuclear Import of Hepatitis B Virus Capsids in the Nuclear Basket
por: Schmitz, André, et al.
Publicado: (2010)

Nucleoporin TPR Affects C2C12 Myogenic Differentiation via Regulation of Myh4 Expression
por: Uhlířová, Jana, et al.
Publicado: (2021)

Tpr is localized within the nuclear basket of the pore complex and has a role in nuclear protein export
por: Frosst, Phyllis, et al.
Publicado: (2002)

ZC3HC1 is a structural element of the nuclear basket effecting interlinkage of TPR polypeptides
por: Gunkel, Philip, et al.
Publicado: (2022)

Assessing the recovery of steroid levels and gonadal histopathology of tilapia exposed to polystyrene particle pollution by supplementary feed
por: Hayati, Alfiah, et al.
Publicado: (2022)

Biophysical Evaluation of Water-Soluble Curcumin Encapsulated in β-Cyclodextrins on Colorectal Cancer Cells
por: Low, Zhi Xuan, et al.
Publicado: (2022)

Major Binding Sites for the Nuclear Import Receptor Are the Internal Nucleoporin Nup153 and the Adjacent Nuclear Filament Protein Tpr
por: Shah, Sundeep, et al.
Publicado: (1998)

ZC3HC1 Is a Novel Inherent Component of the Nuclear Basket, Resident in a State of Reciprocal Dependence with TPR
por: Gunkel, Philip, et al.
Publicado: (2021)

The Regulation of Hypoxia Inducible Factor (HIF)1α Expression by Quercetin: an In Silico Study
por: Wahyuningsih, Sri Puji Astuti, et al.
Publicado: (2022)

Volumetric growth analysis of an insular dysembryoplastic neuroepithelial tumor over a 10-year follow-up
por: Uno, Takehiro, et al.
Publicado: (2016)

Tumor Microenvironment in Glioma Invasion
por: Tamai, Sho, et al.
Publicado: (2022)

NSP9 of SARS-CoV-2 attenuates nuclear transport by hampering nucleoporin 62 dynamics and functions in host cells
por: Makiyama, Kei, et al.
Publicado: (2022)

Basket Ball
Publicado: (1965)

Basket Ball
Publicado: (1965)

Biological basis and clinical study of glycogen synthase kinase- 3β-targeted therapy by drug repositioning for glioblastoma
por: Furuta, Takuya, et al.
Publicado: (2017)

The Multiple Faces of Disordered Nucleoporins
por: Lemke, Edward A.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_gavriqh1nego4fbkjfcap8d0f8