Protection of the C. elegans germ cell genome depends on diverse DNA repair pathways during normal proliferation

Maintaining genome integrity is particularly important in germ cells to ensure faithful transmission of genetic information across generations. Here we systematically describe germ cell mutagenesis in wild-type and 61 DNA repair mutants cultivated over multiple generations. ~44% of the DNA repair mu...

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Detalles Bibliográficos
Autores principales: Meier, Bettina, Volkova, Nadezda V., Hong, Ye, Bertolini, Simone, González-Huici, Víctor, Petrova, Tsvetana, Boulton, Simon, Campbell, Peter J., Gerstung, Moritz, Gartner, Anton
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8078821/
https://www.ncbi.nlm.nih.gov/pubmed/33905417
http://dx.doi.org/10.1371/journal.pone.0250291

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8078821/
https://www.ncbi.nlm.nih.gov/pubmed/33905417
http://dx.doi.org/10.1371/journal.pone.0250291

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