Drug reformulation for a neglected disease. The NANOHAT project to develop a safer more effective sleeping sickness drug

BACKGROUND: Human African trypanosomiasis (HAT or sleeping sickness) is caused by the parasite Trypanosoma brucei sspp. The disease has two stages, a haemolymphatic stage after the bite of an infected tsetse fly, followed by a central nervous system stage where the parasite penetrates the brain, cau...

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Detalles Bibliográficos
Autores principales: Sanderson, Lisa, da Silva, Marcelo, Sekhar, Gayathri N., Brown, Rachel C., Burrell-Saward, Hollie, Fidanboylu, Mehmet, Liu, Bo, Dailey, Lea Ann, Dreiss, Cécile A., Lorenz, Chris, Christie, Mark, Persaud, Shanta J., Yardley, Vanessa, Croft, Simon L., Valero, Margarita, Thomas, Sarah A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8078842/
https://www.ncbi.nlm.nih.gov/pubmed/33857146
http://dx.doi.org/10.1371/journal.pntd.0009276

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