Molecular Profiling-Based Assignment of Cancer Therapy (NCI-MPACT): A Randomized Multicenter Phase II Trial

PURPOSE: This trial assessed the utility of applying tumor DNA sequencing to treatment selection for patients with advanced, refractory cancer and somatic mutations in one of four signaling pathways by comparing the efficacy of four study regimens that were either matched to the patient's aberr...

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Detalles Bibliográficos
Autores principales: Chen, Alice P., Kummar, Shivaani, Moore, Nancy, Rubinstein, Lawrence V., Zhao, Yingdong, Williams, P. Mickey, Palmisano, Alida, Sims, David, O'Sullivan Coyne, Geraldine, Rosenberger, Christina L., Simpson, Mel, Raghav, Kanwal P. S., Meric-Bernstam, Funda, Leong, Stephen, Waqar, Saiama, Foster, Jared C., Konaté, Mariam M., Das, Biswajit, Karlovich, Chris, Lih, Chih-Jian, Polley, Eric, Simon, Richard, Li, Ming-Chung, Piekarz, Richard, Doroshow, James H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Clinical Oncology 2021
Materias:
ORIGINAL REPORTS
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8078898/
https://www.ncbi.nlm.nih.gov/pubmed/33928209
http://dx.doi.org/10.1200/PO.20.00372

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