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Inhalation delivery dramatically improves the efficacy of topotecan for the treatment of local and distant lung cancer

Topotecan is potent anti-cancer drug approved for various malignancies but hematopoietic toxicities undermine its wider application and use of its most effective dose. This study aims to improve these limitations through inhalation-delivery. The pharmacokinetics, efficacy, and toxicity of 2–5 times...

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Detalles Bibliográficos
Autores principales:	Kuehl, Philip J., Yingling, Christin M., Dubose, Devon, Burke, Michael, Revelli, David A., Chen, Wenshu, Dye, Wendy W., Belinsky, Steven A., Tessema, Mathewos
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8079036/ https://www.ncbi.nlm.nih.gov/pubmed/33860729 http://dx.doi.org/10.1080/10717544.2021.1912209

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