Cargando…

Synergy and allostery in ligand binding by HIV-1 Nef

The Nef protein of human and simian immunodeficiency viruses boosts viral pathogenicity through its interactions with host cell proteins. By combining the polyvalency of its large unstructured regions with the binding selectivity and strength of its folded core domain, Nef can associate with many di...

Descripción completa

Detalles Bibliográficos
Autores principales:	Aldehaiman, Abdullah, Momin, Afaque A., Restouin, Audrey, Wang, Luyao, Shi, Xiaoli, Aljedani, Safia, Opi, Sandrine, Lugari, Adrien, Shahul Hameed, Umar F., Ponchon, Luc, Morelli, Xavier, Huang, Mingdong, Dumas, Christian, Collette, Yves, Arold, Stefan T.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Portland Press Ltd. 2021
Materias:	Structural Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8079166/ https://www.ncbi.nlm.nih.gov/pubmed/33787846 http://dx.doi.org/10.1042/BCJ20201002

Ejemplares similares

Passenger sequences can promote interlaced dimers in a common variant of the maltose-binding protein
por: Momin, Afaque A., et al.
Publicado: (2019)

The exceptionally efficient quorum quenching enzyme LrsL suppresses Pseudomonas aeruginosa biofilm production
por: Rehman, Zahid Ur, et al.
Publicado: (2022)

H-NS uses an autoinhibitory conformational switch for environment-controlled gene silencing
por: Shahul Hameed, Umar F, et al.
Publicado: (2019)

ContaMiner and ContaBase: a webserver and database for early identification of unwantedly crystallized protein contaminants
por: Hungler, Arnaud, et al.
Publicado: (2016)

Versatile control of the CDC48 segregase by the plant UBX-containing (PUX) proteins
por: Zhang, Junrui, et al.
Publicado: (2021)

A Biochemical/Biophysical Assay Dyad for HTS-Compatible Triaging of Inhibitors of the HIV-1 Nef/Hck SH3 Interaction
por: Breuer, Sebastian, et al.
Publicado: (2013)

Thicker Ice Improves the Integrity and Angular Distribution of CDC48A Hexamers on Cryo-EM Grids
por: Huntington, Brandon, et al.
Publicado: (2022)

Endogenous Control Mechanisms of FAK and PYK2 and Their Relevance to Cancer Development
por: Naser, Rayan, et al.
Publicado: (2018)

CRISPR directed evolution of the spliceosome for resistance to splicing inhibitors
por: Butt, Haroon, et al.
Publicado: (2019)

Decoding the mechanisms of allostery
por: Khan, Saif, et al.
Publicado: (2023)

Virus assembly, allostery and antivirals
por: Zlotnick, Adam, et al.
Publicado: (2011)

Convergent allostery in ribonucleotide reductase
por: Thomas, William C., et al.
Publicado: (2019)

Rational design of Striga hermonthica-specific seed germination inhibitors
por: Zarban, Randa A, et al.
Publicado: (2021)

Ack1: Activation and Regulation by Allostery
por: Gajiwala, Ketan S., et al.
Publicado: (2013)

Modulation of allostery by protein intrinsic disorder
por: Ferreon, Allan Chris M., et al.
Publicado: (2013)

NMR Methods to Study Dynamic Allostery
por: Grutsch, Sarina, et al.
Publicado: (2016)

Possible mechanism and clinical potentials of allostery
por: Huang, Peixin, et al.
Publicado: (2014)

Photoprogramming Allostery in Human Serum Albumin
por: Putri, Rindia M., et al.
Publicado: (2018)

Synergistic Allostery in Multiligand-Protein Interactions
por: Ghode, Abhijeet, et al.
Publicado: (2020)

GMP Synthetase: Allostery, Structure, and Function
por: Ballut, Lionel, et al.
Publicado: (2023)

Dynamic allostery in thrombin—a review
por: Komives, Elizabeth A.
Publicado: (2023)

Structural basis for specific inhibition of the highly sensitive ShHTL7 receptor
por: Shahul Hameed, Umar, et al.
Publicado: (2018)

Evolution of allostery in the cyclic nucleotide binding module
por: Kannan, Natarajan, et al.
Publicado: (2007)

Allostery and instability in the functional plasticity of synaptotagmin I
por: Fealey, Michael E., et al.
Publicado: (2013)

A Unified View of “How Allostery Works”
por: Tsai, Chung-Jung, et al.
Publicado: (2014)

Allostery through protein-induced DNA bubbles
por: Traverso, Joseph J., et al.
Publicado: (2015)

Insights into the molecular mechanism of allostery in Hsp70s
por: Mayer, Matthias P., et al.
Publicado: (2015)

Allostery of DNA nanostructures controlled by enzymatic modifications
por: Yan, Qi, et al.
Publicado: (2020)

Allostery and Epistasis: Emergent Properties of Anisotropic Networks
por: Campitelli, Paul, et al.
Publicado: (2020)

Allostery in the nitric oxide dioxygenase mechanism of flavohemoglobin
por: Gardner, Anne M., et al.
Publicado: (2020)

Structural Basis for Allostery in PLP-dependent Enzymes
por: Tran, Jenny U., et al.
Publicado: (2022)

HIV-1 Envelope Conformation, Allostery, and Dynamics
por: Bennett, Ashley Lauren, et al.
Publicado: (2021)

Allostery through DNA drives phenotype switching
por: Rosenblum, Gabriel, et al.
Publicado: (2021)

AlphaFold, Artificial Intelligence (AI), and Allostery
por: Nussinov, Ruth, et al.
Publicado: (2022)

HIV-1 Nef: at the crossroads
por: Foster, John L, et al.
Publicado: (2008)

A Conserved GPG-Motif in the HIV-1 Nef Core Is Required for Principal Nef-Activities
por: Martínez-Bonet, Marta, et al.
Publicado: (2015)

Crystal structure of unliganded TRAP: implications for dynamic allostery
por: Malay, Ali D., et al.
Publicado: (2011)

Linkage and Allostery in snRNP Protein/RNA Complexes
por: Williams, Sandra G., et al.
Publicado: (2014)

Design of protein switches based on an ensemble model of allostery
por: Choi, Jay H., et al.
Publicado: (2015)

The Allostery Landscape: Quantifying Thermodynamic Couplings in Biomolecular Systems
por: Cuendet, Michel A., et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_6jd9mtrfh1to5mnmok5bkb2thq